ID A0A0L0KDW7_9ACTN Unreviewed; 486 AA.
AC A0A0L0KDW7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=GntR family transcriptional regulator {ECO:0000313|EMBL:KND36018.1};
GN ORFNames=IQ63_13460 {ECO:0000313|EMBL:KND36018.1};
OS Streptomyces acidiscabies.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=42234 {ECO:0000313|EMBL:KND36018.1, ECO:0000313|Proteomes:UP000037151};
RN [1] {ECO:0000313|Proteomes:UP000037151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 4445 {ECO:0000313|Proteomes:UP000037151};
RA Harrison J., Sapp M., Thwaites R., Studholme D.J.;
RT "Genome sequencing of plant-pathogenic Streptomyces species.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND36018.1}.
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DR EMBL; JPPY01000084; KND36018.1; -; Genomic_DNA.
DR RefSeq; WP_050370883.1; NZ_KQ257815.1.
DR AlphaFoldDB; A0A0L0KDW7; -.
DR PATRIC; fig|42234.21.peg.2773; -.
DR OrthoDB; 594134at2; -.
DR Proteomes; UP000037151; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR PRINTS; PR00035; HTHGNTR.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000037151};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 21..89
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 486 AA; 52281 MW; AD0368CD23A9497C CRC64;
MASSGTSPWE VLRPAVTAPA RTRGRTVQEA LREAIRAGRL AAGTRLPSSR DLAADLGVSR
GLVTEAYEQL TAEGYLRSGR GAGTWVGDAV RAAAPRARDR APRSPGARAD FVPGSPDLSL
FPRAAWSAAQ RAVLAGLPHQ DLGYPDPRGL PRLRTALAAL LTRRRGVVAD PERLIVVSGV
AQALALLGGA LHARGIREVG VEDPGSPPHA ALYEAAGLDV VPLPLDDDGL ALGPLHHARV
RTVVTTPAHQ FPTGIAYAPE RRTRLLEWAR AVDGFVLEDD YDGDFRYDRD PVGALQGLDP
ERVAYTGSVS KSLAPGLRLG WLLLPEALAE DVTERKRTAD LGHPALDQAV FARFVEHGDY
DRHLRRCGRA YRERRDTLVA SLADHFPGTE VSGIAAGLHV IATLPERYGP QERFLERVTE
AGVEVRALTE YGHARVDDDS HLAPSSSYPR ARVQSDVRPR LVLGYAHLTP IRIRTGVALM
ARAAGG
//
