ID A0A0L0KPC9_9ACTN Unreviewed; 277 AA.
AC A0A0L0KPC9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 41.
DE RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN Name=sigD_3 {ECO:0000313|EMBL:GAQ54287.1};
GN Synonyms=sigD_4 {ECO:0000313|EMBL:GAV40874.1};
GN ORFNames=a10_04094 {ECO:0000313|EMBL:GAQ54287.1}, IQ63_03515
GN {ECO:0000313|EMBL:KND39460.1}, Saa2_03774
GN {ECO:0000313|EMBL:GAV40874.1};
OS Streptomyces acidiscabies.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=42234 {ECO:0000313|EMBL:KND39460.1, ECO:0000313|Proteomes:UP000037151};
RN [1] {ECO:0000313|EMBL:KND39460.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=NCPPB 4445 {ECO:0000313|EMBL:KND39460.1};
RA Chen X.-L., Norrbom A., Zhu C.-D.;
RT "A systematic study of Ichneumonosoma Meijere, Pelmatops Enderlein,
RT Pseudopelmatops Shiraki and Soita Walker (Diptera: Tephritidae).";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000037151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCPPB 4445 {ECO:0000313|Proteomes:UP000037151};
RA Harrison J., Sapp M., Thwaites R., Studholme D.J.;
RT "Genome sequencing of plant-pathogenic Streptomyces species.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000058287, ECO:0000313|Proteomes:UP000186713}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=a10 {ECO:0000313|Proteomes:UP000058287}, A2
RC {ECO:0000313|EMBL:GAV40874.1}, and a2
RC {ECO:0000313|Proteomes:UP000186713};
RG Cross-ministerial Strategic Innovation Promotion Program (SIP) consortium;
RA Tomihama T., Ikenaga M., Sakai M., Okubo T., Ikeda S.;
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:GAQ54287.1, ECO:0000313|Proteomes:UP000058287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A10 {ECO:0000313|EMBL:GAQ54287.1}, and a10
RC {ECO:0000313|Proteomes:UP000058287};
RA Tomihama T., Nishi Y., Sakai M., Ikenaga M., Okubo T., Ikeda S.;
RT "Draft Genome Sequences of Streptomyces scabiei S58, Streptomyces
RT turgidiscabies T45, and Streptomyces acidiscabies a10, the Pathogens of
RT Potato Common Scab, Isolated in Japan.";
RL Genome Announc. 4:e00062-16(2016).
RN [5] {ECO:0000313|Proteomes:UP000058287}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=a10 {ECO:0000313|Proteomes:UP000058287}, A2
RC {ECO:0000313|EMBL:GAV40874.1}, and a2
RC {ECO:0000313|Proteomes:UP000186713};
RA Tomihama T., Ikenaga M., Sakai M., Okubo T., Ikeda S.;
RT "Draft genome of pathogenic Streptomyces sp. in Japan.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Sigma factors are initiation factors that promote the
CC attachment of RNA polymerase to specific initiation sites and are then
CC released. {ECO:0000256|RuleBase:RU362124}.
CC -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC {ECO:0000256|RuleBase:RU362124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KND39460.1}.
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DR EMBL; BCMK01000032; GAQ54287.1; -; Genomic_DNA.
DR EMBL; BCML01000027; GAV40874.1; -; Genomic_DNA.
DR EMBL; JPPY01000023; KND39460.1; -; Genomic_DNA.
DR RefSeq; WP_029183874.1; NZ_PCGS01000640.1.
DR AlphaFoldDB; A0A0L0KPC9; -.
DR STRING; 42234.IQ63_03515; -.
DR GeneID; 33084248; -.
DR PATRIC; fig|42234.21.peg.723; -.
DR eggNOG; COG1191; Bacteria.
DR OrthoDB; 9799825at2; -.
DR Proteomes; UP000037151; Unassembled WGS sequence.
DR Proteomes; UP000058287; Unassembled WGS sequence.
DR Proteomes; UP000186713; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:InterPro.
DR GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR CDD; cd06171; Sigma70_r4; 1.
DR Gene3D; 1.10.1740.10; -; 1.
DR Gene3D; 1.20.140.160; -; 1.
DR InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR InterPro; IPR000943; RNA_pol_sigma70.
DR InterPro; IPR007627; RNA_pol_sigma70_r2.
DR InterPro; IPR007624; RNA_pol_sigma70_r3.
DR InterPro; IPR007630; RNA_pol_sigma70_r4.
DR InterPro; IPR012845; RNA_pol_sigma_FliA_WhiG.
DR InterPro; IPR013325; RNA_pol_sigma_r2.
DR InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR NCBIfam; TIGR02479; FliA_WhiG; 1.
DR NCBIfam; TIGR02937; sigma70-ECF; 1.
DR PANTHER; PTHR30385:SF7; RNA POLYMERASE SIGMA FACTOR FLIA; 1.
DR PANTHER; PTHR30385; SIGMA FACTOR F FLAGELLAR; 1.
DR Pfam; PF04542; Sigma70_r2; 1.
DR Pfam; PF04539; Sigma70_r3; 1.
DR Pfam; PF04545; Sigma70_r4; 1.
DR PIRSF; PIRSF000770; RNA_pol_sigma-SigE/K; 1.
DR PRINTS; PR00046; SIGMA70FCT.
DR SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR PROSITE; PS00715; SIGMA70_1; 1.
DR PROSITE; PS00716; SIGMA70_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW Reference proteome {ECO:0000313|Proteomes:UP000037151};
KW Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU362124};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU362124}.
FT DOMAIN 76..89
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00715"
FT DOMAIN 242..268
FT /note="RNA polymerase sigma-70"
FT /evidence="ECO:0000259|PROSITE:PS00716"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 277 AA; 30792 MW; 95FF0E63627F40D0 CRC64;
MPQHTSGSDR TAVPPAARDG GSVRPAPSTL DELWRSYKET GDERLREQLI LHYSPLVKYV
AGRVSVGLPP NVEQADFVSS GIFGLIDAIE KFDVDREIKF ETYAITRIRG AMIDELRALD
WIPRSVRQKA RNVERAYATL EARLRRTPSE QEVAAELGIA VEDLHAVFSQ LSLANVVALD
ELLHVGSESG LSFVDTLEDH AADNPVEVAE DRELRRFLAR AINTLPDREK TVVTLYYYEG
LTLAEIGNVL GVTESRVSQI HTKSVLQLRA KLAGFGR
//
