ID A0A0L1IBX6_PLAFA Unreviewed; 1704 AA.
AC A0A0L1IBX6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=DNA repair protein REV1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFMG_03380 {ECO:0000313|EMBL:KNG77156.1};
OS Plasmodium falciparum IGH-CR14.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=580059 {ECO:0000313|EMBL:KNG77156.1, ECO:0000313|Proteomes:UP000054562};
RN [1] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054562}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=IGH-CR14 {ECO:0000313|Proteomes:UP000054562};
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Godfrey P., Alvarado L.,
RA Berlin A., Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M.,
RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C.,
RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., Roberts A.,
RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T.,
RA White J., Yandava C., Wirth D.F., Nusbaum C., Birren B.;
RT "The genome sequence of Plasmodium falciparum IGH-CR14.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; GG665260; KNG77156.1; -; Genomic_DNA.
DR EnsemblProtists; KNG77156; KNG77156; PFMG_03380.
DR Proteomes; UP000054562; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR CDD; cd03468; PolY_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF00817; IMS; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000054562}.
FT DOMAIN 235..310
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 667..829
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 148..174
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1034..1055
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1509..1531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..174
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1704 AA; 203883 MW; 5B3E9D051D697536 CRC64;
MDIEYGGARD FEKYICNKEE KIPLSYNKKY LAEIEESHKK CKNDSLLFMN CNFYIDDFVS
FFSICNTLDN SNTQTKCIYR NEKDSVEDSK ELNNYMNNNS INKTTLGKFN MENKMEYNYT
SINEHNNNNY YINKIHNDSV FKYQDMDKTP MKNNIDNNSN NNNNNNDNNN NNGNTYLYDN
YLEDQFNQTI KNRYSCTPND QISTCTKSFN TCIKTYEEQA SSSCKKNVYN SYINKKENLE
ILIVQNGGVI HNTLTSKVTH IISNNMALGS KKYMDYKKAI KKSKVFIVID QYIFDCVNMQ
CRLPEQSYLP SMLRYNCHQI TEYFSLRKKD KEQNKKMQNK KIQDKINNDQ NFLKEHKEGE
QNNVTILDTS KCDKQLNDYY VEKKLSTCHN KTSVNNNLNK TDMYGTKEDN NLLIHKDIGN
NENLNYINEQ KVREENNNEE KKENITNNDN INKHLEILNM NMDYEHVKKF IICNSNEYFK
RLQEYYLEKE LKENIYSNVS SNLYLNKNTF EDFCRKYRIL NYLSDEEIKW LKCKSELNIN
IKNLWENDII HFFFDLVLRK KEHFKNNTVG NNNIGNNHNI GNNNNIGNNH NIGNNNNNIG
NNNNNTQSYT DINKSSSYIC ENLIESISAY LYNSRLYILG NWNYISKELF NFDDIKEYEK
GSKKFVYLYI DFDNYFLNAS IRNKICMYEK KKSMNNEIFC VCHSLKKEDS YGIISSTNYW
GKKNKILKGM VKGEATKMNK NINFVKYDFS NILKCSYLFL LVLINYSKNV RVLSVDESIL
QLFYEKEEDI FIISKKISDD IYRLTNLSVS IGISHDLSTS RKALKFCKKR FMFFDFYHHF
NIFIKKYISL KNKESNITPE ASNDDNIKSN TISDDKIING KLKHMIEQNK NVNGTNNTDD
YRTNWMSDDK LKDLFKEYLS FEKKRKSELK YNENNKEKYN MNIDNIYFMN LIKGKREKEV
EYIYNKFLEM NKENIEQMVN TYFEEVIHPV STYFFFYKPN EYYFNILKNM NYLNGYFISF
NMYYLPHIEN DSNNNNNNNN HHHSNNNLHS NNNFHSNNNF HSNNNWLNNK MDRNINKKEL
ENNDEKKSIN ISVNYGVRFN KINDFYYLIY FMTKQLYLRL KIKNLKAKLL HVNFFIKAEN
ENVNPMKYLG RGRVIRISSK IKLNQHTNCF FVYFFKVIHT FDFLANNLSD LRGVQIICSD
TINENKTHVN KKSILYYFYV NTEKNIKNKK NCKYVASWKD DNFLEVPQKV NDKDQVQENV
KDPHQINENK IHLHNIMLSS QKKNETNKKE TNGKISKNNI NSSSILSYIK DKNKGTNILT
SQINWTHSNN NNNNNTYSRK EIRKTVRKGT STSIKRKIKN KINTHIRYDK NIRNNKLYHY
EYKQNILNYF VHNNHNSNRT QNLIHKKENN FQNNQNVSLC SSSKTINKGF KRKCNILRSN
ANFLNIRKKI KITKNYKISD FFPSILKKKI YIRNNKNIYD DEIKTYGNGN IIMHTNIFDS
IINKKIKKEN DEENDEENDE ENEENEQNEK NEKNELCDKN YHMKKQFTCC YFCYKEITQY
LVHKEKLFEE NHKCNDLCRN DIFCFTYICN NLLLFNHTND KLNLYLYIKK IINSYRSYFH
NTFEEHDCVC NNTLKKDQEN IYYLNKFMVK VIDDICEMLH KKRYIDVLQN FLKNFKYVWS
LNNELFPEIF QRILIKYNIN HMTT
//
