ID A0A0L1J9J0_ASPNO Unreviewed; 308 AA.
AC A0A0L1J9J0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Dihydrodipicolinate synthase {ECO:0008006|Google:ProtNLM};
GN ORFNames=ANOM_004295 {ECO:0000313|EMBL:KNG88419.1};
OS Aspergillus nomiae NRRL 13137.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus.
OX NCBI_TaxID=1509407 {ECO:0000313|EMBL:KNG88419.1, ECO:0000313|Proteomes:UP000037505};
RN [1] {ECO:0000313|EMBL:KNG88419.1, ECO:0000313|Proteomes:UP000037505}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 13137 {ECO:0000313|EMBL:KNG88419.1,
RC ECO:0000313|Proteomes:UP000037505};
RA Moore M.G., Shannon B.M., Brian M.M.;
RT "The Genome of the Aflatoxigenic Filamentous Fungus Aspergillus nomius.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DapA family.
CC {ECO:0000256|PIRNR:PIRNR001365}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNG88419.1}.
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DR EMBL; JNOM01000053; KNG88419.1; -; Genomic_DNA.
DR RefSeq; XP_015409342.1; XM_015549552.1.
DR AlphaFoldDB; A0A0L1J9J0; -.
DR STRING; 1509407.A0A0L1J9J0; -.
DR GeneID; 26806099; -.
DR OrthoDB; 1705410at2759; -.
DR Proteomes; UP000037505; Unassembled WGS sequence.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd00408; DHDPS-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR002220; DapA-like.
DR PANTHER; PTHR12128:SF73; 4-HYDROXY-TETRAHYDRODIPICOLINATE SYNTHASE; 1.
DR PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR Pfam; PF00701; DHDPS; 1.
DR PIRSF; PIRSF001365; DHDPS; 1.
DR PRINTS; PR00146; DHPICSNTHASE.
DR SMART; SM01130; DHDPS; 1.
DR SUPFAM; SSF51569; Aldolase; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000256|PIRNR:PIRNR001365};
KW Reference proteome {ECO:0000313|Proteomes:UP000037505}.
FT ACT_SITE 139
FT /note="Proton donor/acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT ACT_SITE 167
FT /note="Schiff-base intermediate with substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT BINDING 51
FT /ligand="pyruvate"
FT /ligand_id="ChEBI:CHEBI:15361"
FT /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ SEQUENCE 308 AA; 33241 MW; 901A2622F51B5B51 CRC64;
MRNTRNIFEG LVAFPITPTD SHGIVNTATL GRIIERLDIP GVDSIGLLGS TGTYMYLTRA
QRKRALDAAI QTLQGRKPLI VSVGALRTDD AQQLAKDAEE AGADGLLLAP VSYNPLSEEE
VYQHYESVTG STTLPLCIYN TPSTTHFTFS DTLLACIAGL PNVVALKQPA PASEATERHE
ALRAKLPSGF SIGYSADWLV ADSLLAGGSA WYSVIAGVLP APSVALMAAI RKGDDIEVRR
ISALFQPMWD LFEELSDLKV AFALANELDL CKAAPPRPIL PIAASHHNRI RSALARLNEG
IKEMPWKI
//
