ID A0A0L6CT00_9RHOB Unreviewed; 808 AA.
AC A0A0L6CT00;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=4-methylaminobutanoate oxidase (Formaldehyde-forming) {ECO:0000313|EMBL:KNX40897.1};
DE EC=1.5.3.19 {ECO:0000313|EMBL:KNX40897.1};
GN Name=mlr_5 {ECO:0000313|EMBL:KNX40897.1};
GN ORFNames=ROTO_25850 {ECO:0000313|EMBL:KNX40897.1};
OS Roseovarius tolerans.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Roseovarius.
OX NCBI_TaxID=74031 {ECO:0000313|EMBL:KNX40897.1, ECO:0000313|Proteomes:UP000037046};
RN [1] {ECO:0000313|Proteomes:UP000037046}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EL-164 {ECO:0000313|Proteomes:UP000037046};
RA Voget S., Bruns H., Wagner-Doebler I., Schulz S., Daniel R.;
RT "Draft Genome Sequence of Roseovarius tolerans EL-164, a producer of N-
RT Acylated Alanine Methyl Esters (NAMEs).";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GcvT family.
CC {ECO:0000256|ARBA:ARBA00008609}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNX40897.1}.
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DR EMBL; LGVV01000037; KNX40897.1; -; Genomic_DNA.
DR RefSeq; WP_050663444.1; NZ_LGVV01000037.1.
DR AlphaFoldDB; A0A0L6CT00; -.
DR STRING; 74031.SAMN04488077_10161; -.
DR PATRIC; fig|74031.6.peg.2637; -.
DR OrthoDB; 7156675at2; -.
DR Proteomes; UP000037046; Unassembled WGS sequence.
DR GO; GO:0102317; F:4-methylaminobutyrate oxidase (demethylating) activity; IEA:UniProtKB-EC.
DR Gene3D; 2.40.30.110; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.70.1400; Aminomethyltransferase beta-barrel domains; 1.
DR Gene3D; 3.30.9.10; D-Amino Acid Oxidase, subunit A, domain 2; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR006076; FAD-dep_OxRdtase.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR032503; FAO_M.
DR InterPro; IPR013977; GCV_T_C.
DR InterPro; IPR006222; GCV_T_N.
DR InterPro; IPR029043; GcvT/YgfZ_C.
DR InterPro; IPR027266; TrmE/GcvT_dom1.
DR PANTHER; PTHR13847:SF187; DIMETHYLGLYCINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR13847; SARCOSINE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF01266; DAO; 1.
DR Pfam; PF16350; FAO_M; 1.
DR Pfam; PF01571; GCV_T; 1.
DR Pfam; PF08669; GCV_T_C; 1.
DR SUPFAM; SSF101790; Aminomethyltransferase beta-barrel domain; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR SUPFAM; SSF103025; Folate-binding domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:KNX40897.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000037046}.
FT DOMAIN 7..364
FT /note="FAD dependent oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF01266"
FT DOMAIN 367..421
FT /note="FAD dependent oxidoreductase central"
FT /evidence="ECO:0000259|Pfam:PF16350"
FT DOMAIN 425..692
FT /note="Aminomethyltransferase folate-binding"
FT /evidence="ECO:0000259|Pfam:PF01571"
FT DOMAIN 733..800
FT /note="Glycine cleavage T-protein C-terminal barrel"
FT /evidence="ECO:0000259|Pfam:PF08669"
SQ SEQUENCE 808 AA; 89041 MW; D5726865474888AA CRC64;
MKTHAQAVVI GGGVIGCSIL YHLAKLGWSD VVLLERDELT SGSTWHAAAN IHGLHDSANI
SRLQHYTMNL YNALEEETGQ SCGVFQPGSL YLAQTENRSH QLRLQAAKAK LYGMNFHEIS
RDEAERLHPL VNFDGIRCIM YEPDGGNVDP SGVTNAYAVG ARQRGAEIHR FTPVMATVPQ
ADGTWIVETP KGNIHTPWVI NAAGLWGREV AKLAGIELPL QPTEHQYFVT ETIAEIAGMD
RRLPSVADRD GEYYLRQEGK GLLIGAYERD MRFWAEEGTP LDFAHDLFPD DLERIEDNMM
RAIDRVPVVG EAGIKRVING PMIWSPDANV ILGPVPELKG YFCCNGIIPG FSQSAGMGWM
VAEWLVHGEM KYDMFAWDIA RFGLWANDRE FVKAKVKDQY AHRFAIHYPN EERAAGRPLR
VRPAYEMQKD MGAVFGLNYG WEHPLWFSEV PGTVDTNGFT RQNWWGPVGE EARMLRERAG
IIDISNFAKY RVKGPGAEEW LNAVFANRMP RAVGRSCLTP LIGVRGGIAG DATVTRLGEE
EFWVISSGMA ERYHKRFFDA VPLPEGTVFE SLTEAVCGFN VAGPRSREML QRLTNASLST
EDFAFMRSAK IEIAGVSCVA LRVSFTGDLG WELHCATEDQ ARLYAALIEA GREMGAGPVG
SRALMSLRIE KGYGSWSREY SPEYWPQEAG LAGLCKMDKD FLNKAALEAV IGEAPRERLV
LLALEAADVM ASNADATGGE PIFKDGVGVG RVTSGAYGYA VGMSLALGYV KGGAGPGDAV
EVMVLGQPHR ARILHEPPFD PEGVRLRA
//
