ID   A0A0L6T6U4_9BURK        Unreviewed;       454 AA.
AC   A0A0L6T6U4;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Membrane fusion protein (MFP) family protein {ECO:0000256|RuleBase:RU365093};
GN   ORFNames=AD742_15330 {ECO:0000313|EMBL:KNZ31881.1};
OS   Methylibium sp. NZG.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Sphaerotilaceae; Methylibium.
OX   NCBI_TaxID=1686064 {ECO:0000313|EMBL:KNZ31881.1, ECO:0000313|Proteomes:UP000053102};
RN   [1] {ECO:0000313|Proteomes:UP000053102}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Bi G.;
RT   "Draft Genome Sequences of the MTBE Degrading Bacterium Methylibium sp.
RT   NZG.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000256|RuleBase:RU365093}; Single-pass membrane protein
CC       {ECO:0000256|RuleBase:RU365093}.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477, ECO:0000256|RuleBase:RU365093}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KNZ31881.1}.
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DR   EMBL; LGRD01000028; KNZ31881.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L6T6U4; -.
DR   STRING; 1686064.AD742_15330; -.
DR   PATRIC; fig|1686064.3.peg.4441; -.
DR   Proteomes; UP000053102; Unassembled WGS sequence.
DR   GO; GO:0019898; C:extrinsic component of membrane; IEA:InterPro.
DR   GO; GO:1990195; C:macrolide transmembrane transporter complex; IEA:InterPro.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR   GO; GO:1990961; P:xenobiotic detoxification by transmembrane export across the plasma membrane; IEA:InterPro.
DR   Gene3D; 2.40.30.170; -; 1.
DR   Gene3D; 2.40.50.100; -; 1.
DR   Gene3D; 6.10.140.1990; -; 1.
DR   InterPro; IPR030190; MacA_alpha-hairpin_sf.
DR   InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR   InterPro; IPR006144; Secretion_HlyD_CS.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   InterPro; IPR010129; T1SS_HlyD.
DR   NCBIfam; TIGR01843; type_I_hlyD; 1.
DR   PANTHER; PTHR30386:SF25; MANNURONAN SYNTHASE; 1.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   Pfam; PF13533; Biotin_lipoyl_2; 1.
DR   Pfam; PF13437; HlyD_3; 1.
DR   PRINTS; PR01490; RTXTOXIND.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
DR   PROSITE; PS00543; HLYD_FAMILY; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane {ECO:0000256|RuleBase:RU365093};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU365093};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU365093};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053102};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU365093};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU365093};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365093}.
FT   TRANSMEM        45..63
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU365093"
FT   DOMAIN          85..117
FT                   /note="Membrane fusion protein biotin-lipoyl like"
FT                   /evidence="ECO:0000259|Pfam:PF13533"
SQ   SEQUENCE   454 AA;  49410 MW;  1C37684FF2777D35 CRC64;
     MRKLLNPITA RVFGSVPAEL SAADRGFQFE AEAILARQRS RRARAIVYSG VAVCAALGVW
     AHYAHVDEVT RGDAKVVPSR QLQVIQALDG GVVSEILVKE GQQVEAGQLL LRIDQTRATS
     GVRENAAQSF ALLARERRLR ALAEGTAFVP PPAAGNAEQQ RIIDEERRLF EARRSELGTL
     VSISREQLSQ REHELAEARS RRVSAQGAMA LAQQELARTK PLLASGAVSE VEVLRLEREV
     NKNRGDVDQA AAQIARVQAA IGEARRKIEE TDISFRNEAR KELADVMGRA NALVEGQVAL
     TDKVDKALVK SPVRGRVQRL LANTVGGVVQ PGRDIVEVVP LEDALVLDAR VAPKDIAFIH
     PGQVATVKFS AYDFAIYGGL EATVENISPD TVVDDKGNAF YMVRVRTRTP NFGANLPIIP
     GMTAEVDVLT GKKSVLSYLL KPVLRGKAYA LTER
//