ID   A0A0L6TVZ8_9FIRM        Unreviewed;       731 AA.
AC   A0A0L6TVZ8;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   RecName: Full=Metallo-beta-lactamase domain-containing protein {ECO:0000259|SMART:SM00849};
GN   ORFNames=AKG39_17565 {ECO:0000313|EMBL:KNZ40423.1};
OS   Acetobacterium bakii.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Eubacteriaceae;
OC   Acetobacterium.
OX   NCBI_TaxID=52689 {ECO:0000313|EMBL:KNZ40423.1, ECO:0000313|Proteomes:UP000036873};
RN   [1] {ECO:0000313|Proteomes:UP000036873}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 8239 {ECO:0000313|Proteomes:UP000036873};
RA   Song Y., Hwang S., Cho B.-K.;
RT   "Draft genome sequence of Acetobacterium bakii DSM 8293, a potential
RT   psychrophilic chemical producer through syngas fermentation.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KNZ40423.1}.
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DR   EMBL; LGYO01000061; KNZ40423.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L6TVZ8; -.
DR   STRING; 52689.AKG39_17565; -.
DR   Proteomes; UP000036873; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR   CDD; cd07731; ComA-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR035681; ComA-like_MBL.
DR   InterPro; IPR004477; ComEC_N.
DR   InterPro; IPR004797; Competence_ComEC/Rec2.
DR   InterPro; IPR025405; DUF4131.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   NCBIfam; TIGR00360; ComEC_N-term; 1.
DR   NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR   PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR   PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR   Pfam; PF03772; Competence; 1.
DR   Pfam; PF13567; DUF4131; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000036873};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        180..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        209..224
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        276..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..337
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        349..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        385..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        414..435
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        442..461
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          474..678
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   731 AA;  79999 MW;  EB4C5224B862E730 CRC64;
     MAAFPVNDPL ENFYGNDVGI KGVVSGSPVI ESYGVVFNLT AQEVANEPEM IKGPVGLRIT
     LPVQEDETPS LPIPGDLIII NGELSKPQGL RNPGGYDYQL YLKSKGIQGL VYVESGKIET
     VGRDPSIFDG IIGNKTQLET ISAAYLSKDV SDLLNGVVFG EKDIDSEIKL NFQNAGVTHV
     LSVSGLHVGY VFLLISFLLT LLKVKKKHWL FYLIPALFFY AVMTGFEPPV IRASIMLGSL
     TLGQGIHREK DSLNNFCLAG ILILCLWPSQ LFQPGFQLSM GAVLGIIFFY ESLLFEYKKL
     LNKKSVGKAK KPGPIIEGLV LTLCATIGTL PMMFYHFKGF TLLSFVSNLI IVPLIGAFLL
     AGILFLTIAA VFPLAGPLLG MPLNFFGKTI LVTLYGINDI GDALGFLWVK RGGFSIIELL
     LFVYLAFLIA GYYQVRKTWV KNTVVVTGVL LGICLIVLPT FPKNLVMTVL DVGQGDSILI
     ETPGGFNYLI DGGGYYLEKD IGVSERVLLP ALYAKNIKKL DGVFLSHNHV DHSQGVEELL
     EADFPVENLF MSINTNNDKL LNQNVVPINL LKRGSIIEGP DGVKFEILSP DGEVKPLGED
     DQNNASLVIK LSYGKMNFLL CGDIEKEVEA KLIDEINEET RSQDIQVIKI AHHGSKTSST
     QGFLTAVDPE LAVISVGAYN TFGHPSDEVL MRLENTGIKT QRTDENGAVE ITSNGEWINY
     KTFVNSQGEK Q
//