ID A0A0L6V1F3_9BASI Unreviewed; 1245 AA.
AC A0A0L6V1F3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE RecName: Full=DNA mismatch repair protein {ECO:0000256|PIRNR:PIRNR037677};
GN ORFNames=VP01_308g6 {ECO:0000313|EMBL:KNZ53965.1};
OS Puccinia sorghi.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=27349 {ECO:0000313|EMBL:KNZ53965.1, ECO:0000313|Proteomes:UP000037035};
RN [1] {ECO:0000313|EMBL:KNZ53965.1, ECO:0000313|Proteomes:UP000037035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RO10H11247 {ECO:0000313|EMBL:KNZ53965.1,
RC ECO:0000313|Proteomes:UP000037035};
RA Rochi L., Burguener G., Darino M., Turjanski A., Kreff E., Dieguez M.J.,
RA Sacco F.;
RT "Next Generation Sequencing and Analysis of the Genome of Puccinia sorghi L
RT Schw, the Causal Agent of Maize Common Rust.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the post-replicative DNA mismatch repair system
CC (MMR). {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNZ53965.1}.
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DR EMBL; LAVV01008046; KNZ53965.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L6V1F3; -.
DR STRING; 27349.A0A0L6V1F3; -.
DR VEuPathDB; FungiDB:VP01_308g6; -.
DR OrthoDB; 168255at2759; -.
DR Proteomes; UP000037035; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 3.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 2.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361:SF148; DNA MISMATCH REPAIR PROTEIN MSH6; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 5.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PIRNR:PIRNR037677};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PIRNR:PIRNR037677};
KW DNA repair {ECO:0000256|PIRNR:PIRNR037677, ECO:0000256|RuleBase:RU003756};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR037677};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|PIRNR:PIRNR037677};
KW Reference proteome {ECO:0000313|Proteomes:UP000037035}.
FT DOMAIN 1067..1083
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 1..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 100..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..38
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 56..78
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..134
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1245 AA; 139259 MW; 5188BAE16A086ECF CRC64;
MSGSNSKASN KLKQSTLGGF LTKTQPSSSK NPGSEPGTRL NAGYNRDDPD AVDDQDDDVV
LKKPRAGTRD KRKSVVVAGS SSEDELNSGL FLCLSRSRLP ASKKPRYSCA SSASGASTPK
SYGDGFSSHP STAGPSEADD EDVDDEDDNT SNLKPKPFKS SLTVKSKLGL SANNAEKSKS
DGKNSAPWKQ GPWAFLKDIK DADGNPVGSP DYDPRTLYIS KKDWASMTPF EIQFWEIKRS
RLSFFDHFDT VLFFQKGKFS ELYEGDAMIG HQEFDLKITK RVKMVIRYQL HSMVGVPETS
VDFWIAKFLA KGYKVIELSE VSFPFPVLNK SRCPFLLTFA ILQVGKVDQC ETALGAEMRN
KGSLPTSKYA KPPPQQKGSG KEIVRRELRS VVTSGTIVDG NILTDNAATC LLAIKESINS
SDFPVFGVII MDAATAEFNL THFEDSANRT HLETIMSRFK PKEILHEKSG LSPASLRVLR
NTASSDCTWT ALKSDEFLDP EESVCRLTEL FQESGGQIPE VFQSFNDKLE TMQALGGLLW
YLKQLNLDKD LLTCGNVKVL DAFRCSNTMH LDGKTISDLE LLQSDGNEES RLLKLLNRCV
TPFGNNICFC VIHLDLFLRF FLLLQPFKIG KRLFRHWLCS PLQDTDAIRA RLDAVDFLMS
NPSFEQTFGT LSGLPDLERL ISRVHAGACT VPNFLKVLKA FEKIHSTVQE LRQLINETPA
VLLKELLDSL PDNEKLLQNL QDMFTLNDDR RELLPLEGKD ESYDMALEEE NQAEKALGAE
LKAAKKLLKT EDVVYKDIGI KDIYQIQVSA KVKVPSNWTK MSGTKDCARY YSPQSAQLVK
KLKQAREKKT CALKDFHLKV VTRLDSPRTR ERLELTSSHV QVFSAFDNDY LIWLQVVRSV
AQLDCVISLA KALGRGDGQV HHAPTSMHGW ARRQRLHLER CFRGWRRVSH DTPHRPQHVQ
SYTYAINYYE INLGCCQLTV ISIFFLSLIR AGKSTLLRMT CVATILAQIG CYVPAESAAI
SPVDRICTRM GASDHIFAHA STFKGEREIF LEMDDARKII HEATSKSLVI LDELGRGTST
FDGHAIAFAV LHRLATHSNC LGFFATHYSA LTEDFKFHAN IAKKYMLTNV DEVTREVVFL
YKLASGVSPR SYGPHVAKMA GIPHKIVQRA IGISEQFEEE TKSRELSMKK QSGHARLNLL
TLADTAFLLR LVRNGGFDNP ASVRENSNTL HRIFDGLHHL HLSHS
//
