ID A0A0L6V4I6_9BASI Unreviewed; 1131 AA.
AC A0A0L6V4I6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Upf1 domain-containing protein {ECO:0000259|PROSITE:PS51997};
GN ORFNames=VP01_2691g3 {ECO:0000313|EMBL:KNZ55407.1};
OS Puccinia sorghi.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina;
OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia.
OX NCBI_TaxID=27349 {ECO:0000313|EMBL:KNZ55407.1, ECO:0000313|Proteomes:UP000037035};
RN [1] {ECO:0000313|EMBL:KNZ55407.1, ECO:0000313|Proteomes:UP000037035}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RO10H11247 {ECO:0000313|EMBL:KNZ55407.1,
RC ECO:0000313|Proteomes:UP000037035};
RA Rochi L., Burguener G., Darino M., Turjanski A., Kreff E., Dieguez M.J.,
RA Sacco F.;
RT "Next Generation Sequencing and Analysis of the Genome of Puccinia sorghi L
RT Schw, the Causal Agent of Maize Common Rust.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the DNA2/NAM7 helicase family.
CC {ECO:0000256|ARBA:ARBA00007913}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01341}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KNZ55407.1}.
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DR EMBL; LAVV01007603; KNZ55407.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L6V4I6; -.
DR STRING; 27349.A0A0L6V4I6; -.
DR VEuPathDB; FungiDB:VP01_2691g3; -.
DR OrthoDB; 170190at2759; -.
DR Proteomes; UP000037035; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:InterPro.
DR CDD; cd21407; 1B_UPF1-like; 1.
DR CDD; cd18039; DEXXQc_UPF1; 1.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR CDD; cd21400; ZBD_UPF1-like; 1.
DR Gene3D; 2.40.30.230; -; 1.
DR Gene3D; 6.10.140.1240; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR040812; UPF1_1B_dom.
DR InterPro; IPR018999; UPF1_CH/ZBD.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF364; REGULATOR OF NONSENSE TRANSCRIPTS 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF04851; ResIII; 1.
DR Pfam; PF18141; UPF1_1B_dom; 1.
DR Pfam; PF09416; UPF1_Zn_bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51997; UPF1_CH_RICH; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU01341}; Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000037035};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU01341};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU01341}.
FT DOMAIN 114..276
FT /note="Upf1"
FT /evidence="ECO:0000259|PROSITE:PS51997"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 63..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 186..216
FT /note="C4"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01341"
FT REGION 933..973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1078..1131
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1131 AA; 125072 MW; 3395760D0B4A83B1 CRC64;
MENFSHLGGA SEYSYSPAND DDDGLSLVSG STRDALKVNR LQIGDHSEST IDDINFDELS
LLDANPEPTR NRQKANNSSD YDHQSHPELS VESSSRFNSV EGEADFEDVL DDLNRELPSH
ACAYCGIHSP SSVVKCLICS KWFCNSRGGP GAHSTGSHIV NHLVRAKHKE VTLHEDGPLG
ETTPECYNCG SKNVFTLGFI PAKSDTVVVL LCRQPCASTP SSKSDLVWDT SQWSPLIEDR
QFLSWLVKVP DEQEVVRSKP VGFREITRLE EMWKENAMAT LDDLERDGTL GEGEPQPILL
RYEDAYQYQN IFGPLVKIES DYDRKLKESL TQNDVTVRWD MGLNQKRIAY FYLPKLESGE
VRLAVGDELR LRYSGELQQA WEGPGHVIKV PNNQSDEVAL ELRRNEGVPH ELTVNFSVDF
VWKSTSFDRM QMAMKTFAVD DQSVSGYIYR KLLGHEASVP QVLRTQMPKR YSSHCPLFVR
VSAPNLPELN HSQVSAVKSV LQKPLSLVQG PPGTGKTVTS ASVVYHLSKM NPGQVLVCAP
SNVAVDQLTE KIHMTGLKVV RVQAKSREAI DSSVQYLTLH QQVANNDTHP DLQKLIQLKA
EQGELSSTDE RRYKSLTRLC EREILAAADV ILCTCVGAGD PRLAKMKFRT VLIDEATQAT
EPECMIPLTL GVKQVVMVGD HQQLGPTIMN KKAARAGLTQ SMFERLVLLG NRPIRLQVQY
RMHPCLSEFP SNMFYEGSLQ NGVTAPERIK KNVDFPWPQP ATPMCFHCNL GQEEISSSGT
SFLNRTEASN VEKVVTRFFK AGVLPSQIGI VTPYEGQRSY IVTYMQTNGT LKKDLYKDIE
VASVDAFQGR EKDYIILSCV RSNDHQGIGF LNDPRRLNVA LTRAKYGVVV LGNPKVLSKH
ALWHFLLTAY KEKSCLVEGP LNNLQPSLVQ LSKPRKPLDR ADLPVNRFEP NPRELPPLSY
SRNGPTNTPT RFDHSFYKTV DSFSIPSDAQ SVRSQATYAS GLPPFSLPIS RSMGYPNGGK
RVGGGLGSVG VGGSSYASSM ISQDLQSQDS RSVRGADDAS SVADSMADSV AAYSQADRLL
SGRSRNDRTG LDYGAHGGPG PMGVGGSKSY RADDDDARSL ISMQSSSITD F
//
