ID A0A0L6WD94_9AGAR Unreviewed; 1237 AA.
AC A0A0L6WD94;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=Rac guanine nucleotide exchange factor B {ECO:0000313|EMBL:KNZ73490.1};
GN ORFNames=J132_03254 {ECO:0000313|EMBL:KNZ73490.1};
OS Termitomyces sp. J132.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Tricholomatineae; Lyophyllaceae;
OC Termitomyces.
OX NCBI_TaxID=1306850 {ECO:0000313|EMBL:KNZ73490.1, ECO:0000313|Proteomes:UP000053712};
RN [1] {ECO:0000313|Proteomes:UP000053712}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J132 {ECO:0000313|Proteomes:UP000053712};
RA Hu H., Poulsen M.;
RT "The genome of Termitomyces.";
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ412803; KNZ73490.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L6WD94; -.
DR STRING; 1306850.A0A0L6WD94; -.
DR OrthoDB; 53554at2759; -.
DR Proteomes; UP000053712; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR12673:SF270; DH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR12673; FACIOGENITAL DYSPLASIA PROTEIN; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF52075; Outer arm dynein light chain 1; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053712}.
FT DOMAIN 810..1077
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 1..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 449..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 557..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 776..803
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..50
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..136
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..174
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..468
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 469..488
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..512
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 557..595
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 601..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..650
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 776..797
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1237 AA; 134006 MW; 4DB5075F447295D4 CRC64;
MSLPDPSQFP DPYPFRPPHH HLPSVPALSS TSSSSTRSSA YTSSAGGFAS SDYGHANVAS
ADDESTVGVG ITSDAIVQLL AKDSSVSASP RGIQSRTTVD QSRWSESYSN EKSQSSSAGN
NNAGSVPENP RPTLQQKPSY DMGWVDERDE VGMSEEETDD DHPLDDDEQD EEKEEGTSAV
VIAEEGRGLI VQGDNVPITQ LQVPPGTTHL LIGSSSTPNA MPTFLTATLP QIGHSLLALD
ISANFLGALP PVLAVCERLE ELNIAYNPLR VLPVFLADLI NLRVIIADST GISTLPESLA
DLDKLHTISV RKNKLNWLCL LPALNTLCVD GNPFQGPWKA LVEPLLTKMP MPPAYPHSTP
IFTAQCMSIS STNTENTETD TTDIDDLSDS SLVSEHISGH DDEDHTITPA HAAPVLGRSI
TTPLPPTPQI APVAVGLTRT RTTPNRSHFE MSRVKTTQTG NQQDRTSKPT EEFGSDRELR
KMKSAGDLRH GKTTGVAQSG ATPSIRPALS KYPTSVSSSN LLSTLSTGSP EQAGTAKRYA
TNSLARLATN GMRTQVTKSM WDTPSDSVVE DPSPSITSNR VSLAQSSTAS SPAKMSIPDI
QDGKHSNRAR STKDGKEKGS RWGFLKKMSM GKMKVDSPSL SNSQSRVGSR PHTPAEPVPR
NPGSRPERSK TPQIDLRFST TGDSEQYLRR EEERVREAYN RALRSVMAYL KDMNDLGLSQ
QSRAMSMYGA ASDDPVAPRS RRPTMIDGQR EVSMALSGST GSSDSNGQLR SNESIAGLRS
GNSTQTLSIA TTDSTSSSFE ERKFKDDKGK RAMIVREIVA TERTYVKGLQ ELMDIYIKPA
CDTVNILSGV GSNKDTIVPA AERKLVFGGI DALFSFHKDS FLPALEVAAA PLMKSSESLQ
QADADGGLSL SVVKAVGCMF LKHAAFMKMY SSYINNFDNA VSRVKYWTAE RNPQGATSPV
SSAVSPSSST GQLVGVNALS MPASTLDASS ASTGVPNLTS SQRKRIKSYL KRCRLNPRHS
QLNLEGYLLL PVQRIPRYRL LLEELVRSTP PNYEYEDDPL ERALAEISSL ANNMNEGKRE
SESRRKLVQW QSRIRGKFPS PLVQPHRRLI MDGPLLLTRV VRKAMVSFEA INAQGDASTV
QVDCLAPELT PRALVGILCN DLLVLCRDPS GGQDPSSSVD LWAVLRMQTL PQPASIVHGN
ALRLVDNKAI LYFDAPSASD ALNWYRAINL HIPASKT
//
