ID A0A0L7M5X3_PLAF4 Unreviewed; 668 AA.
AC A0A0L7M5X3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=PFDG_00240 {ECO:0000313|EMBL:KOB88226.1};
OS Plasmodium falciparum (isolate Dd2).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=57267 {ECO:0000313|EMBL:KOB88226.1, ECO:0000313|Proteomes:UP000054282};
RN [1] {ECO:0000313|Proteomes:UP000054282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Volkman S.K., Neafsey D.E., Dash A.P., Chitnis C.E., Hartl D.L.,
RA Young S.K., Zeng Q., Koehrsen M., Alvarado L., Berlin A., Borenstein D.,
RA Chapman S.B., Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J.,
RA Griggs A., Gujja S., Heilman E.R., Heiman D.I., Howarth C., Jen D.,
RA Larson L., Mehta T., Neiman D., Park D., Pearson M., Roberts A., Saif S.,
RA Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., White J.,
RA Yandava C., Haas B., Henn M.R., Nusbaum C., Birren B.;
RT "Annotation of Plasmodium falciparum Dd2.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000054282}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG The Broad Institute Genome Sequencing Platform;
RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Henn M., Jaffe D.,
RA Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., Mauceli E.,
RA Brockman W., MacCallum I.A., Rounsley S., Young S., LaButti K.,
RA Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., Engels R.,
RA Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., White J.,
RA Kodira C., Zeng Q., O'Leary S., Yandava C., Alvarado L., Wirth D.,
RA Volkman S., Hartl D.;
RT "The genome sequence of Plasmodium falciparum Dd2.";
RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; GG701597; KOB88226.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L7M5X3; -.
DR SMR; A0A0L7M5X3; -.
DR EnsemblProtists; KOB88226; KOB88226; PFDG_00240.
DR OMA; DEMIIQI; -.
DR Proteomes; UP000054282; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniRule.
DR CDD; cd16499; RING-HC_Bre1-like; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR15898:SF13; RING FINGER PROTEIN PSH1; 1.
DR PANTHER; PTHR15898; UNCHARACTERIZED; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000054282};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 615..654
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 109..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 46..80
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 215..292
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 387..497
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 558..585
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 114..166
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 668 AA; 80991 MW; 43B5A44F4651438A CRC64;
MFFDKFKKDI KSYKQIMYLK NVEFRKYNLD YIRKINYEKC FYYKNYIDIK KKISELQKDN
ESLKIQVDRL EKKKATLIYK LNNDNIRKHI LDNNIKDYQN GIDNSKVSYF DEGENPYNRN
NKNYRTDNKN SDDNNNNNNY YYNNYNSDDN YNSEDNEYNN GNYRFRNNYK KDSLNEDDVK
KNPLNVCHKI NSDSNIFVNF ENIITKQNII HSEPFRNLLK ESNELYITLK EKEKENIILK
NEILKMENKK DEEYEHLLNN TIEDKKELTR SIKELEINMM TCNMEKDKIS NKVNTLEYEI
NVLKNIDKNQ TMQLQQKEND ILKMKLYIEK LKLSEKNLKD KIILLENEKD KMLSGIHIKD
NSFNEESKSE EGKIQLRDIQ NDNDEKYDDE KKRFKELFIE NQKLKEELNK KRNVEEELHS
LRKNYNIINE EIEEITKEFE KKQEQVDEMI LQIKNKELEL LDKFNNKMNK AYVEEKLKEL
KNTYEEKMKH INNIYKKHDD FVNIYLNLFF QARKNAILSD SQREEQMNLF IKLKDKYDII
FQKKIELTDI LKNVYDCNKK LIGHCQDLEK ENSTLQNKLS NEIKNSKMLS KNLSKNSDDH
LLIEENNELR RRLICSVCME NFRNYIIIKC GHIYCNNCIF NNLKTRNRKC PQCKVPFDKK
DLQKIFLD
//
