ID   A0A0L7QS10_9HYME        Unreviewed;       694 AA.
AC   A0A0L7QS10;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   SubName: Full=Mitochondrial intermediate peptidase {ECO:0000313|EMBL:KOC61412.1};
GN   ORFNames=WH47_06681 {ECO:0000313|EMBL:KOC61412.1};
OS   Habropoda laboriosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC   Anthophila; Apidae; Habropoda.
OX   NCBI_TaxID=597456 {ECO:0000313|EMBL:KOC61412.1, ECO:0000313|Proteomes:UP000053825};
RN   [1] {ECO:0000313|EMBL:KOC61412.1, ECO:0000313|Proteomes:UP000053825}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=0110345459 {ECO:0000313|EMBL:KOC61412.1};
RA   Pan H., Kapheim K.;
RT   "The genome of Habropoda laboriosa.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU003435};
CC       Note=Binds 1 zinc ion. {ECO:0000256|RuleBase:RU003435};
CC   -!- SIMILARITY: Belongs to the peptidase M3 family.
CC       {ECO:0000256|ARBA:ARBA00006040, ECO:0000256|RuleBase:RU003435}.
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DR   EMBL; KQ414766; KOC61412.1; -; Genomic_DNA.
DR   RefSeq; XP_017794335.1; XM_017938846.1.
DR   AlphaFoldDB; A0A0L7QS10; -.
DR   STRING; 597456.A0A0L7QS10; -.
DR   EnsemblMetazoa; XM_017938846.1; XP_017794335.1; LOC108575912.
DR   GeneID; 108575912; -.
DR   OrthoDB; 735202at2759; -.
DR   Proteomes; UP000053825; Unassembled WGS sequence.
DR   GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   CDD; cd06457; M3A_MIP; 1.
DR   Gene3D; 3.40.390.10; Collagenase (Catalytic Domain); 1.
DR   Gene3D; 1.10.1370.10; Neurolysin, domain 3; 1.
DR   InterPro; IPR033851; M3A_MIP.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR024077; Neurolysin/TOP_dom2.
DR   InterPro; IPR045090; Pept_M3A_M3B.
DR   InterPro; IPR001567; Pept_M3A_M3B_dom.
DR   PANTHER; PTHR11804:SF79; MITOCHONDRIAL INTERMEDIATE PEPTIDASE; 1.
DR   PANTHER; PTHR11804; PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED; 1.
DR   Pfam; PF01432; Peptidase_M3; 1.
DR   SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003435};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW   ECO:0000256|RuleBase:RU003435};
KW   Metalloprotease {ECO:0000256|ARBA:ARBA00023049,
KW   ECO:0000256|RuleBase:RU003435};
KW   Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|RuleBase:RU003435};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053825};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|RuleBase:RU003435}.
FT   DOMAIN          238..677
FT                   /note="Peptidase M3A/M3B catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01432"
SQ   SEQUENCE   694 AA;  79658 MW;  BFF7F503EDE7E3F5 CRC64;
     MIQVLSKQFP RHFKKHRNVN TWSSLATTFN TVIKEKYGFE FSKKETGLFG IPELKTPEGF
     NILKDQAISQ TDALITESIS ENRKRKMVEI FDDMSDALCK VADLAEFIRI AHPERQFVKA
     AEDSCLFVSS IVEKLNTHRE LYNTLRHAVY NGDILETSVM DNHVATLFLS DFEQSAIHLP
     ESIREDVVQL NYYILQVGQK FMAGAGNTKA IDANIVPHNV RQYFTVKDNK VYVQGLYVDS
     SDCLVRETAY RVFLYPDQEQ EYLLQELLNS RHTLAELCGF PSYVHRAVKG STVETPEVIH
     EFLNILNKNL KPKAKQDFEE MQKMKDAESP IKQKIMPWDT AYFTAKAKKN WLNMSISEFA
     PYFSLGACMD GINILIQALY GIRLEYVPVL SGEVWANNVH KIAVIDENEA ILGYIYCDFF
     EREGKPNQDC HFTIRGGRQL SDGSYQNPIV VLMLSLPLPT WSKPCLLNPA SVENLFHEMG
     HALHSMLGRT KYQHVTGTRC STDFAEVPSV LMEYFASDPR VVFTFAKHFQ TLEKIPTTLL
     EKLYASKNIF CASELQNQIC YSMLDQVYHS GKLEKPSTEI LKEIQGKYYE LPYIENTAWQ
     LRFSHLVGYG AKYYSYLISR AIASWIWQTY FKADPFNRTA GNRYRNECLA HGGGKPPSKL
     VSDFLDKEAN ASNFAKSLLY EIDTKMEHVQ KLRE
//