ID A0A0L7QVQ0_9HYME Unreviewed; 3945 AA.
AC A0A0L7QVQ0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Dynein heavy chain 7, axonemal {ECO:0000313|EMBL:KOC62698.1};
GN ORFNames=WH47_04812 {ECO:0000313|EMBL:KOC62698.1};
OS Habropoda laboriosa.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Habropoda.
OX NCBI_TaxID=597456 {ECO:0000313|EMBL:KOC62698.1, ECO:0000313|Proteomes:UP000053825};
RN [1] {ECO:0000313|EMBL:KOC62698.1, ECO:0000313|Proteomes:UP000053825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0110345459 {ECO:0000313|EMBL:KOC62698.1};
RA Pan H., Kapheim K.;
RT "The genome of Habropoda laboriosa.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC {ECO:0000256|ARBA:ARBA00008887}.
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DR EMBL; KQ414722; KOC62698.1; -; Genomic_DNA.
DR STRING; 597456.A0A0L7QVQ0; -.
DR Proteomes; UP000053825; Unassembled WGS sequence.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46961; DYNEIN HEAVY CHAIN 1, AXONEMAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR46961:SF9; DYNEIN HEAVY CHAIN, CYTOPLASMIC-LIKE PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000256|ARBA:ARBA00023273};
KW Cilium {ECO:0000256|ARBA:ARBA00023069};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053825}.
FT DOMAIN 683..1086
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1215..1541
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 1707..1855
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 2075..2168
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2234..2496
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT DOMAIN 2510..2852
FT /note="Dynein heavy chain coiled coil stalk"
FT /evidence="ECO:0000259|Pfam:PF12777"
FT DOMAIN 2881..3102
FT /note="Dynein heavy chain ATP-binding dynein motor region"
FT /evidence="ECO:0000259|Pfam:PF12781"
FT DOMAIN 3346..3459
FT /note="Dynein heavy chain region D6 P-loop"
FT /evidence="ECO:0000259|Pfam:PF03028"
FT DOMAIN 3494..3633
FT /note="Dynein heavy chain AAA lid"
FT /evidence="ECO:0000259|Pfam:PF18198"
FT DOMAIN 3639..3941
FT /note="Dynein heavy chain C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18199"
FT COILED 608..668
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2744..2799
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 3945 AA; 454384 MW; 1EFA4F8367E86107 CRC64;
MECDCEEVTS CEGIPHPVVQ KERAKPVQKI SNVIDRKIEP FMVGLIAKTE LPGVNIDLNN
DKDVNRYYNY ICNGVDTVHA VKIQDDILRM ILSLVPSHLR GRFEYLTEGL LFEIKAIFTE
NIKKAILEYA LRDPMEDYLS QEKTTQNLLK IKRSLPGLSA AVQGNRETLR QILYLINPCM
RMSLEHWVGN FRDFRLFDLK QIAEHERSWD LLEFEKTIHK HIVKARKVLR DSWYSGIQDI
FLVNNRKQLV PSPLQRTRFK GFYDCIAKIM ESQLLAMCKW TLRDFMDLII RGQPIDCEFN
VDIVVSSNQL TFSPSFEEFK EVLCGLLDEI CQAIRRFHKL QTQLYLDWSG PEEILKPQID
ESIVEKLKRE IIDLIDRERI IPEQILMDLQ MYEHLYNDEE YKMIERYVKD ENKKLDDYNE
AMRCYEEQVL NLPVQIERTA FTGLFKVSRK IFVEAIVANV RRIKSLLTDT LVDRYQDTAK
KYKCKVNLTV NVLTIANEFI RVIDNDEHRF RAAEEYQAIS DRALSAPANT AELMDLKSFM
KTVIDVSLKN LEQDLCEIIV HILLLSDYRC LTDVEISTNN IAFQWYHKVP QILEENEVIV
ANKTIEFQQA LKVRYVRFEE ELESYAKQVD EIQYWGDIED VHKYQKRTQN LENRLIAAME
KIDKFNEEET SFGWDITQYP RRKQIADHLK PYKQLFDAIC DFLTKHDLWI NTMIGSYNPE
DIDNDVGYAY RTIYKLEKAF QEPDLKELAG NVREKIEEFR ERMPIVFTLG NPGLKARHWD
EISAIIGVPI KVDADLTLAR ILDMGLDLFV EKFESISDSA SKESTLERAM DKMQKDWTDL
AFTVNPFKDT GTFVIAGVDD IQLLLDDHII KTVTIKNSPN IKPFEARILR WEYKMHLLQD
ILDQWLRVQA VWMYLEPIFT SPDIQQQMPD EGRKFSAVDK TWRDIMKTVE TDPRVLAVIE
IDKMLERLKK SYGLLEDIQK GLNDYLEKKR LFFPRFFFLS NDELLEILSE TKDPTRVQPH
LKKCFEGIST LKFNEDLEVL AMRSTEGEEV PLVDVISTAS ARGQVEKWLV ELETIMRRSV
KHEVKHAIDA YPMKQRKIWV LEWPGQTILC VGKMYWTLRI EESMLFGEEG LWRYFDQCTT
ELNEIILLIR GKLSKQNRIT LEALVTLDVH GKDVLSKICK DKVIKNTDFR WLCHLRYYWL
EENMWAYMIN SYQRYGYEYL GNSSRLVITP LTDRCYRTLF GALSLHLGGA PEGPAGTGKT
ETTKDLAKAV AKQCVVFNCS EGLDYIALGK FFKGLASCGA WSCFDEFNRI DLEVLSVVAQ
QILTIQRGIN SGAEKMVFEG TEIFLDPSCA IFITMNPGYA GRSELPDNLK ALFRPVAMMV
PDYALIAENT LYSYGFYNGR PLAVKIVTAY RLCSEQLSSQ HHYDYGMRAV KSVLIAAGNL
KLRYPEESED ILMLRSILDV NLPKFLVHDL PLFEGIASDL FPGVVLPTPD YTHLNACIGE
ACVAANIQCT NFFLEKIQQI YEMMIVRHGF MIVGLPFGGK TSAYRMLADC LALLEERNLM
EEHRVEITVI NPKAITMGQL YGQFDPASHE WSDGVLAVSY RSFASSTNLN RKWLVFDGPV
DAIWIENMNT VLDDNKKLCL TSGEIIQLAP TTNLIFEPMD LEVASPATVS RCGMIYMEPV
SLGWTPLLIS WLNTLPSTFS EHLKNHLNDM YMRFCPPLLE LLRWKVKELM TMPDANLLRS
ITYLFDCFLD DFHDEKYLQT LSDLDMRAQV EGCFFFSCIW AMGGTLTVDS REPFSDLFRA
LTEREFPEDI RERFDVSPET TDPPKPYVVN LPLTGLVFDY KYIKEGRGKW RPWMDDLQDV
PPIPKDVPVN QIIVPTIETV RYFHLFKLLI CHQKPVLLVG PTGTGKSVYI MEFLLKKIDP
DIFKPLFVIF SAQTTANQTQ EIIMSKLDRR RKGLYGAPPG KHWVVFVDDI SMPQKEEYGA
QPPIELLRQW LDHWTWYDVK EVAPIELVDV QLVCAMGPPS SGLDVTPRFK RHFFTLGISE
FSDEVLTTIF TAIVTWHFRV KEFSDIFMFS TEYIVNGTLS VYKEIRKHLL PTPAKCHYLF
NLRDFSRVIQ GVLLSAPETV SDPVGLKRLW VHEVLRVYGD RLVDDVDIRW LVEQIRRTMS
AHMDDHLDTL FQELLIGAEN NQVTEMELRN LVYCDFQDPL ADKKLYMEVS DLDYLAIIVE
EYLAEYNSIS RTPMNLVLFR FAVEHLSKIC RVMMQPRSHA LLIGVGGSGR QSLTKLASHI
ADYELFQVEM SQQYGLHEWH EDLKGILKKS AASDLHTVFL FMDTQVKEET FLEDISNLLN
SGEVPNIFPA DELTDICEKM RAIDRQRDRS MQTDGSPVAL FNFFVQTVRE HLHVVVTMSP
IGDNFRVRIR KFPALVNCCT IDWLQPWPED ALLAVATKFL GEIDLTHDER AACIEMCQFF
HTSTQELSHE FLKKARRYNY VTPTSYLQLI STFKDLLAKK RQEAIDGKRR YEAGLEKLDS
THKQVEKMQE ILVALQPKLL VAAKDVEAMF LDVQRESEEA AAMEQIVKRD EEAAMVVAHE
ADTIRAECDA DLQEVMPILN AANAALNTLT PQDIQIVRSM KRPPAGVRLV MEAVCILKDV
KPEKVKTPEG TVDDYWKASL RMLSDMKFLE SLLTFDKDNI PERIMNKIRS TILTNPNFDP
ERIRNVSTAC EGLCRWVFAL SEYDKVAKIV APKKQALALA EADYDNAMTQ LNLKRSQLQE
VQNRLAKLEE LLNQRKAEYK AMTDEVNECE AKLRRAKELI GGLGGEYTRW SETAKALGER
YYTLTGDILI GSGVVAYLGV FTTQYRQEQI DNWVHICMDL RVVCTKDYQL TQILGDPVLI
RSWNIFGLPS DLFSIDNGII VMNSRRWPLM IDPQGQANKW VKNMEKENNV NVIRLVQSDY
MRVLENAIQF GQPVLLENVG EELDAALEPL LMKQTFKSGG TECIKVGDSI IEYSSNFRFY
ITTKLRNPHY LPEVAVKVTL LNFMITPIGL EDQLLGIVVA KERPDLEAEK NQLIVQGAAN
KKKLKEIEDE ILEVLSTSEG NILEDETAIS VLSSSKNLSD EILKKQTAAE ITEKSIDAAR
LEYTPIAVYS AVLFFTTAVL ANIDPMYQYS LVWFVNLFKN TIDNTEPVED IQQRLKDLTK
HFTYSLYVNI CRSLFEKDKL LFSVLLSVNL LNKQGQLSIP QWMFLLTGGV GLDNPFVNPT
EWLPSKSWDE LCRLDNVPGL EGFKDSFTKN LNAWKFVFDH MEPHILTFPA PYSELTPFER
MLVLRCIRPD KVVPAAQQFV EEQLGRLYIE PPPFDLVSSF ADSYSCIPLI FVLTPGADPM
AILLKFADDQ GFGTNRLFSL SLGQGQGVIA AQLIDDGVKN GTWVVLQNCH LAKSFMPLLE
KICESFTPGT VHPDFRLWLT SYPVDHFPVS VLQNGVKMTN EPPKGLRANI VRSFLQDPIC
DEDFFETSKQ KETFKKLLFS LCFFHAIVQE RRKFGPIGWN NQYEFNETDL RISALQLKIF
LDQYDDVQFT ALKYLTGECN YGGRVTDEWD RRTLNTILER FYRMELIARK KYLFDPSGIY
YVPQATSHNE YLEYIRSFPM ITAPSVFGMN ENADIIKDQQ ETALMLSSIL STQDTGETET
DTGKSPDEVV YGVASDILSK LPGNFDLVDA LEKYPTLYNQ SMNTVLVQEM GRFNKLLQTI
RNSLINVQRA IKGLVIMNPD LEEVYVSIIT GKIPKMWMKN SYPSLKPLGS YVQDFLKRLA
FLQQWYDDGP PTTFWISGFY FTQAFLTGAR QNYARKYSIP IDLLIYDFVP LSETDFPEPP
ADGVYVYGLF LDGASFNLTT MKLDESLPKI LYDNVPYIWM IPMKKEQVPE RKTYTCPVYK
TSERKGVLST TGHSTNFVIA MWLPTEHPPE HWILRGVAML CQLSD
//
