ID A0A0L7R9J6_9HYME Unreviewed; 508 AA.
AC A0A0L7R9J6;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=RBR-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012251};
DE EC=2.3.2.31 {ECO:0000256|ARBA:ARBA00012251};
GN ORFNames=WH47_10493 {ECO:0000313|EMBL:KOC67542.1};
OS Habropoda laboriosa.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Apoidea;
OC Anthophila; Apidae; Habropoda.
OX NCBI_TaxID=597456 {ECO:0000313|EMBL:KOC67542.1, ECO:0000313|Proteomes:UP000053825};
RN [1] {ECO:0000313|EMBL:KOC67542.1, ECO:0000313|Proteomes:UP000053825}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=0110345459 {ECO:0000313|EMBL:KOC67542.1};
RA Pan H., Kapheim K.;
RT "The genome of Habropoda laboriosa.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.;
CC EC=2.3.2.31; Evidence={ECO:0000256|ARBA:ARBA00001798};
CC -!- SIMILARITY: Belongs to the RBR family. Ariadne subfamily.
CC {ECO:0000256|ARBA:ARBA00005884}.
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DR EMBL; KQ414624; KOC67542.1; -; Genomic_DNA.
DR RefSeq; XP_017787680.1; XM_017932191.1.
DR RefSeq; XP_017787681.1; XM_017932192.1.
DR RefSeq; XP_017787682.1; XM_017932193.1.
DR RefSeq; XP_017787683.1; XM_017932194.1.
DR RefSeq; XP_017787684.1; XM_017932195.1.
DR RefSeq; XP_017787685.1; XM_017932196.1.
DR RefSeq; XP_017787686.1; XM_017932197.1.
DR RefSeq; XP_017787687.1; XM_017932198.1.
DR AlphaFoldDB; A0A0L7R9J6; -.
DR STRING; 597456.A0A0L7R9J6; -.
DR EnsemblMetazoa; XM_017932191.1; XP_017787680.1; LOC108570350.
DR EnsemblMetazoa; XM_017932192.1; XP_017787681.1; LOC108570350.
DR EnsemblMetazoa; XM_017932193.1; XP_017787682.1; LOC108570350.
DR EnsemblMetazoa; XM_017932194.1; XP_017787683.1; LOC108570350.
DR EnsemblMetazoa; XM_017932195.1; XP_017787684.1; LOC108570350.
DR EnsemblMetazoa; XM_017932196.1; XP_017787685.1; LOC108570350.
DR EnsemblMetazoa; XM_017932197.1; XP_017787686.1; LOC108570350.
DR EnsemblMetazoa; XM_017932198.1; XP_017787687.1; LOC108570350.
DR GeneID; 108570350; -.
DR OrthoDB; 3084186at2759; -.
DR Proteomes; UP000053825; Unassembled WGS sequence.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR CDD; cd20343; BRcat_RBR_HHARI-like; 1.
DR CDD; cd20356; Rcat_RBR_HHARI-like; 1.
DR CDD; cd16626; RING-HC_RBR_HHARI; 1.
DR Gene3D; 1.20.120.1750; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR045840; Ariadne.
DR InterPro; IPR048962; ARIH1-like_UBL.
DR InterPro; IPR031127; E3_UB_ligase_RBR.
DR InterPro; IPR002867; IBR_dom.
DR InterPro; IPR044066; TRIAD_supradom.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR11685:SF212; E3 UBIQUITIN-PROTEIN LIGASE ARIH1; 1.
DR PANTHER; PTHR11685; RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING; 1.
DR Pfam; PF21235; ARI1_UBAl; 1.
DR Pfam; PF19422; Ariadne; 1.
DR Pfam; PF01485; IBR; 2.
DR SMART; SM00647; IBR; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57850; RING/U-box; 3.
DR PROSITE; PS51873; TRIAD; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053825};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 134..345
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS51873"
FT DOMAIN 138..186
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 59267 MW; 2CB018225031E256 CRC64;
MDSEEETYDD VDSGNESSGD DVDFAMEIEV GNPRERATDV DDYPFEVLST EEIVQHMVDS
IKEVNTVVEI PATTTRILLN HFKWDKEKLM ERFYDGDQEK LFAEARVVNP FSKDPLINRS
RSFQSSLSRR TSNGTEECGI CFTIQPSAMM TGLECGHRFC TGCWGEYLTT KIMEEGVGQT
IACAAHACDI LVDDASVMRL VKDSKVKLKY QHLITNSFVE CNRLLRWCPS PDCNNAIKVQ
YVEARPVTCK CGHTFCFHCG ENWHDPVKCH LLRKWIKKCD DDSETSNWIA ANTKECPKCN
VTIEKDGGCN HMVCKNQNCK TDFCWVCLGP WEPHGSSWYN CNRYDEEEAK AARDAQEKSR
SVLQRYLFYC NRYMNHMQSL KFESKLYASV KEKMEEMQQH NMSWIEVQFL KKAVDILCSC
RQTLMYTYVF AYYVRKNNQS VIFEDNQKDL EGTTERLSEY LERDITSENL ADIKQKVQDK
YRYCDSRRKV LLEHVHEGYE KDWWDYVE
//
