ID   A0A0L8FH02_OCTBM        Unreviewed;       844 AA.
AC   A0A0L8FH02;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE            EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN   ORFNames=OCBIM_22022313mg {ECO:0000313|EMBL:KOF62681.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF62681.1};
RN   [1] {ECO:0000313|EMBL:KOF62681.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF62681.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF62681.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ432663; KOF62681.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L8FH02; -.
DR   EnsemblMetazoa; Ocbimv22022312m; Ocbimv22022312m.p; Ocbimv22022313m.g.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR000961; AGC-kinase_C.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR017892; Pkinase_C.
DR   InterPro; IPR000719; Prot_kinase_dom.
DR   InterPro; IPR008271; Ser/Thr_kinase_AS.
DR   PANTHER; PTHR22988:SF71; CITRON RHO-INTERACTING KINASE; 1.
DR   PANTHER; PTHR22988; MYOTONIC DYSTROPHY S/T KINASE-RELATED; 1.
DR   Pfam; PF00069; Pkinase; 1.
DR   Pfam; PF00433; Pkinase_C; 1.
DR   SMART; SM00133; S_TK_X; 1.
DR   SMART; SM00220; S_TKc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS51285; AGC_KINASE_CTER; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW   Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          85..349
FT                   /note="Protein kinase"
FT                   /evidence="ECO:0000259|PROSITE:PS50011"
FT   DOMAIN          350..420
FT                   /note="AGC-kinase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51285"
FT   REGION          376..395
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          415..444
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          463..511
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          559..651
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          716..835
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        415..433
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   844 AA;  97802 MW;  014C6705EF548674 CRC64;
     MDNESMDSIT SRIQKLEKLM QGEIQEAGIL DSLVNHQGLL DCLYVLFNEC QTQNLLKNKY
     VYEFVKKYKK TVQEIAKLRL KATDFEVKEI IGRGHFGEVR VVRERYSGTV HAMKMLEKSK
     TLAQSDVSFF SEEKEIMAKA DSCWITKLHY TFQDANYLYF VMEFYPGGDL LSLLSRYNDI
     FDEKMARFYL TEMVLAINAV HSLGYIHRDI KPENVLLDRN GHIRLADFGS AAKMSSKNLV
     SSHIPVGTPD YVAPELLKMN TASSVQRYSV EVDWWSLGVC GYEMLYGVTP FSSSDNSKSV
     TYNKIMNYQH YLKFPSSEIS KDAVDLLQHL LTEAKYRLNY QSLLVHPFFA TMNWQNIRNE
     KSPFIPSVSS LDDTSNFDEY ERLPPQPKYD DPKLRRDFSG KDLPFVGFSY FGSTKDESTD
     SSGVTSGVTS SEFDESSDDG KPSNVKLTLT VNVKEHQKIA ERCNELESNE SLLRAELEEL
     RHVVDRKELT IQRLQEDKLS LTKDLSNCAD KSNVLAKRLE QEIEAKDRVH KQGLSILNDI
     NKFNSEAEDI KCAITHAKLD ELKQVIKVLE GQNSAMVKQL FNKDRTLIEC QKHLLSTQEQ
     LEKAKDRLEK DLNHQNAKTS KCHICHDGKL LNKAEKLTED MSKKYEDENK LRIHLEKKLD
     EQLKKQMTND KWLSDSTESL KDELAENQKT IAHQDKLIKE LLEKADNQEM TWKRISEDLE
     LKIKVLEDES NKLRTKEKSN AELKLSLLQQ VNTYQEEVKQ LRNQLQAVTD KITREEESVT
     LELENKIEEL RKQLEKQSNE KELSYEREKQ HLRKIKELEN ILDDKENLKA NNEQRLLTKI
     KVSV
//