ID A0A0L8FHD7_OCTBM Unreviewed; 737 AA.
AC A0A0L8FHD7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Cullin family profile domain-containing protein {ECO:0000259|PROSITE:PS50069};
GN ORFNames=OCBIM_22020391mg {ECO:0000313|EMBL:KOF63074.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF63074.1};
RN [1] {ECO:0000313|EMBL:KOF63074.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF63074.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF63074.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
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DR EMBL; KQ431646; KOF63074.1; -; Genomic_DNA.
DR RefSeq; XP_014789803.1; XM_014934317.1.
DR AlphaFoldDB; A0A0L8FHD7; -.
DR STRING; 37653.A0A0L8FHD7; -.
DR EnsemblMetazoa; Ocbimv22020391m; Ocbimv22020391m.p; Ocbimv22020391m.g.
DR EnsemblMetazoa; XM_014934317.1; XP_014789803.1; LOC106883347.
DR OMA; CQEQMEI; -.
DR OrthoDB; 5474206at2759; -.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF177; CULLIN-2; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 384..614
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
SQ SEQUENCE 737 AA; 86371 MW; 42A5780A038889E6 CRC64;
MSLKPRKVDF NATWQILLET VRGVITCGQV ARSIWNDRFS DVYALCVAVP ESYSDRLYEE
IKNFAENHVE CLYKTVRNDS NILSAYHKHW QEYSQGSIYL NQLFGYLNTT YIKKQKLSDA
DLAYGSFNYE ASDQKLEIGE LCLDIWKRHM IEPLKLQLIL LILQEIQKDR NGGYVNQAVL
HGVINSFVNV EEYKKKEQVQ FYRKLFETRF LQETGEYYKQ EAAKLKVEFN CSEYMEKVIQ
KLGQENLRSR KFLHPSSYEK VTHETQERMV ADHIYFLHAA CEDMVQSERR KDLSNMYVLL
KPIHNGLNYL IDQVESYIRE TGLNAVQDLK GDNVPCMFVE SMLEVHKKYT ELIQSVFNND
QKFIQALDKA CAAAINNKFK GECKSPELLA KYNDNLLKKS SKGISESELD EKLDNCITVF
KYLEDKDIYQ RFYSRMLAKR LIYNASTSMD AEESMINKLK QACGYEFTNK LHQMFTDMTI
SKDLDKKFED YYKNKDIDIG IGFSILVLQA GAWPIRQSGF PTFAIPQELE KSVRMFEMFY
NKNFSGRKLT WMHYSCLADV RFNYLKKTYT VTMGTYHMAI LLLFNNAESL TFRELMDSSQ
LPEKELSKQL QVLVESKIIL TENEINENST LHLNKNYSNK RLRFRISMMQ KLTPQEVAHT
HTSVDNDRKM YLQAAIVRIM KARKVSRHNL LIDEVIKQSK SRFTPSVSLI KKCVETLIDR
QYLERSPNQA DEYVYVA
//
