ID A0A0L8GCK1_OCTBM Unreviewed; 1126 AA.
AC A0A0L8GCK1;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=c-SKI SMAD4-binding domain-containing protein {ECO:0000259|SMART:SM01046};
DE Flags: Fragment;
GN ORFNames=OCBIM_22035832mg {ECO:0000313|EMBL:KOF74643.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF74643.1};
RN [1] {ECO:0000313|EMBL:KOF74643.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF74643.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF74643.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the SKI family. {ECO:0000256|ARBA:ARBA00009513}.
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DR EMBL; KQ422569; KOF74643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8GCK1; -.
DR STRING; 37653.A0A0L8GCK1; -.
DR EnsemblMetazoa; Ocbimv22035832m; Ocbimv22035832m.p; Ocbimv22035832m.g.
DR EnsemblMetazoa; XM_014926783.1; XP_014782269.1; LOC106877775.
DR OMA; QEYINDV; -.
DR GO; GO:0046332; F:SMAD binding; IEA:InterPro.
DR CDD; cd21080; DHD_Skor; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 3.10.260.20; Ski; 1.
DR InterPro; IPR014890; c-SKI_SMAD4-bd_dom.
DR InterPro; IPR009061; DNA-bd_dom_put_sf.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR003380; SKI/SNO/DAC.
DR InterPro; IPR037000; Ski_DNA-bd_sf.
DR InterPro; IPR023216; Tscrpt_reg_SKI_SnoN.
DR PANTHER; PTHR10005:SF26; CORL; 1.
DR PANTHER; PTHR10005; SKI ONCOGENE-RELATED; 1.
DR Pfam; PF08782; c-SKI_SMAD_bind; 1.
DR Pfam; PF02437; Ski_Sno; 1.
DR SMART; SM01046; c-SKI_SMAD_bind; 1.
DR SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR SUPFAM; SSF63763; SAND domain-like; 1.
PE 3: Inferred from homology;
FT DOMAIN 377..470
FT /note="c-SKI SMAD4-binding"
FT /evidence="ECO:0000259|SMART:SM01046"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 54..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 751..872
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 884..1126
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..117
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 138..169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..189
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 190..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..658
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 751..769
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 770..792
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..824
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..863
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 977..1030
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1048..1068
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1069..1101
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1126
FT /evidence="ECO:0000313|EMBL:KOF74643.1"
SQ SEQUENCE 1126 AA; 123740 MW; 9E361412EBFE52B4 CRC64;
MTSKTHCLGN IDKELQRPVS ADGQQSQYLQ SLSHTPHHLA HQSSIINSSS TAGIITSSGS
SGSSGSSSSG NNSSNLISNN NSSSSNTLHT AIGSGSGSNN GNNNSNISIN SHHHPHSSHI
VSPIRSIVGG GGGSGGGGGA GSSSQNGSTT TANNNNSSSS SSSNKAHSNL HLHPHPHHHH
HHHHHHHYNN SNSNSSNSSS SSSNSGINTN TTTNNNNNSN GSNNSNSSNH NSLTASSTTT
TTGSGSGNNG NNNNSINNGK GSPKEYVPTH QNQIGNVILA GVPIVSLFID SKERLCLAQI
SNTLLNKYSY NEIHNRRVAL GITCVQCTPV QLEMLRRAGA MPVSSRRCGM ITKREAERLV
RSFLEENTPP KLPEDFSFNV YHECGWGCQG NFHPSRYNSS RAKCIKCNFC NLFFSPNKFI
FHFHRTANSK YNHPDAANFN SWRRHLKLYG ANTEKEEIVY AWEDVKAMFN GGGRKRFQGS
TSNTHNPKSI GNSVEQAAKR TKLDCGSDIG VSRTGNTVAT NNPSATVKER SPYPMPDCSP
FSMFSNHVRN PSYQTQASYG LSISSTNNAD QLIPTIANNP WASNQTNFLM ATYDRFWASQ
LGLTRQTSEY QNNPYFTKAI PRRDIKLSNE VSKPLNMTPS SSEEEDSGTS SSNEEDLNKP
PTVGHRLSAF RPVNPANSRP KSVEELDRTP LDMKRIGSSL VERSPLMVDS NIENSYDAQD
DTCVEIDVLN EGDDKCSQSD MVKDLCDMRA GSRTDIDDGT DVNGIDDVID HEGDDNDDDD
DDEDDGSDDG GDHGDEDIVN NDHHRDDGDG GSGGGSRGRG HDEEDDVDDN DNENDNNNNN
DDDNNNNNNN NNNNNNNDNN NDTDNASDVE KCRQQNRDRY KLSTEQHQTT LQRQTSPSQQ
QQQQQQQLQH QSQQQQKPQQ QQQQQPQQQQ QQQQLLLQQT HHHQQAQTPP PTLILSSQKQ
QHKPQQSQQQ QQQLHLHEQH LKVEVSDDER DARSMEYSSR KRKHEALKDI EGGGSNLKAE
MKRDEMSPLP KRGIGVRLGG GGGGDIDDEQ EYINDVVDDV DDDDHDRDDD GGVSGGRGRG
GRHRGDDNDD DDNETRHKSM AEPEMNLGNM DRVGMYHPHV RPITDK
//
