ID A0A0L8GFI9_OCTBM Unreviewed; 195 AA.
AC A0A0L8GFI9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=DNA replication complex GINS protein PSF1 {ECO:0000256|RuleBase:RU368085};
GN ORFNames=OCBIM_22034279mg {ECO:0000313|EMBL:KOF75776.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF75776.1};
RN [1] {ECO:0000313|EMBL:KOF75776.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF75776.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF75776.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for correct functioning of the GINS complex, a
CC complex that plays an essential role in the initiation of DNA
CC replication, and progression of DNA replication forks. GINS complex
CC seems to bind preferentially to single-stranded DNA.
CC {ECO:0000256|RuleBase:RU368085}.
CC -!- SUBUNIT: Component of the GINS complex.
CC {ECO:0000256|RuleBase:RU368085}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU368085}.
CC -!- SIMILARITY: Belongs to the GINS1/PSF1 family.
CC {ECO:0000256|ARBA:ARBA00006677, ECO:0000256|RuleBase:RU368085}.
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DR EMBL; KQ422015; KOF75776.1; -; Genomic_DNA.
DR RefSeq; XP_014781453.1; XM_014925967.1.
DR AlphaFoldDB; A0A0L8GFI9; -.
DR STRING; 37653.A0A0L8GFI9; -.
DR EnsemblMetazoa; Ocbimv22034279m; Ocbimv22034279m.p; Ocbimv22034279m.g.
DR EnsemblMetazoa; XM_014925967.1; XP_014781453.1; LOC106877156.
DR GeneID; 106877156; -.
DR KEGG; obi:106877156; -.
DR OMA; NHLCMRR; -.
DR OrthoDB; 166901at2759; -.
DR GO; GO:0000811; C:GINS complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR CDD; cd11710; GINS_A_psf1; 1.
DR CDD; cd21696; GINS_B_Psf1; 1.
DR Gene3D; 1.20.58.1030; -; 1.
DR InterPro; IPR021151; GINS_A.
DR InterPro; IPR036224; GINS_bundle-like_dom_sf.
DR InterPro; IPR005339; GINS_Psf1.
DR PANTHER; PTHR12914:SF2; DNA REPLICATION COMPLEX GINS PROTEIN PSF1; 1.
DR PANTHER; PTHR12914; PARTNER OF SLD5; 1.
DR Pfam; PF05916; Sld5; 1.
DR SUPFAM; SSF158573; GINS helical bundle-like; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU368085};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU368085}.
FT DOMAIN 24..109
FT /note="GINS subunit"
FT /evidence="ECO:0000259|Pfam:PF05916"
SQ SEQUENCE 195 AA; 22716 MW; 95DDC6E0884095EB CRC64;
MLGNKALELI KELSRASSGT LSSYNEDCIR QILDEMKTLY ELNQKDVNDT VAGEAGLFSS
VQVRHAALER NKRCLLTYLY RRLRNIQQMR WEFGSVLPAE IRYNMCEREV QWFNRYNKML
ATYMRNIAGG IGLDLTQDIQ PPKSLYIEVR CLVDHGEFET QDGNIVVLKR NNQHFLLRSE
CENLIRQGIL EHVTN
//
