ID A0A0L8GNY0_OCTBM Unreviewed; 71 AA.
AC A0A0L8GNY0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=glycine hydroxymethyltransferase {ECO:0000256|ARBA:ARBA00012256};
DE EC=2.1.2.1 {ECO:0000256|ARBA:ARBA00012256};
DE AltName: Full=Glycine hydroxymethyltransferase {ECO:0000256|ARBA:ARBA00032953};
DE AltName: Full=Serine methylase {ECO:0000256|ARBA:ARBA00031137};
DE Flags: Fragment;
GN ORFNames=OCBIM_22030569mg {ECO:0000313|EMBL:KOF78574.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF78574.1};
RN [1] {ECO:0000313|EMBL:KOF78574.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF78574.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF78574.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC Evidence={ECO:0000256|ARBA:ARBA00001933};
CC -!- PATHWAY: One-carbon metabolism; tetrahydrofolate interconversion.
CC {ECO:0000256|ARBA:ARBA00004777}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ421025; KOF78574.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8GNY0; -.
DR STRING; 37653.A0A0L8GNY0; -.
DR EnsemblMetazoa; Ocbimv22030569m; Ocbimv22030569m.p; Ocbimv22030569m.g.
DR OMA; NICHHEV; -.
DR UniPathway; UPA00193; -.
DR GO; GO:0004372; F:glycine hydroxymethyltransferase activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0019264; P:glycine biosynthetic process from serine; IEA:InterPro.
DR GO; GO:0035999; P:tetrahydrofolate interconversion; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR001085; Ser_HO-MeTrfase.
DR InterPro; IPR039429; SHMT-like_dom.
DR PANTHER; PTHR11680; SERINE HYDROXYMETHYLTRANSFERASE; 1.
DR PANTHER; PTHR11680:SF35; SERINE HYDROXYMETHYLTRANSFERASE, CYTOSOLIC; 1.
DR Pfam; PF00464; SHMT; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE 4: Predicted;
FT DOMAIN 17..71
FT /note="Serine hydroxymethyltransferase-like"
FT /evidence="ECO:0000259|Pfam:PF00464"
FT NON_TER 71
FT /evidence="ECO:0000313|EMBL:KOF78574.1"
SQ SEQUENCE 71 AA; 8118 MW; 8C4D64D694CBAA73 CRC64;
MSTTNGYEGW CLQDDISQND PQMYEFIKQE KLRQKQGLEM IASENFTSKA VMQALGSCLT
NKYSEGYPGQ R
//
