ID A0A0L8GV85_OCTBM Unreviewed; 581 AA.
AC A0A0L8GV85;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=FZ domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=OCBIM_22027137mg {ECO:0000313|EMBL:KOF80971.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF80971.1};
RN [1] {ECO:0000313|EMBL:KOF80971.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF80971.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF80971.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00090}.
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DR EMBL; KQ420199; KOF80971.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8GV85; -.
DR EnsemblMetazoa; Ocbimv22027137m; Ocbimv22027137m.p; Ocbimv22027137m.g.
DR EnsemblMetazoa; XM_014922209.1; XP_014777695.1; LOC106874472.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd07066; CRD_FZ; 2.
DR Gene3D; 1.10.2000.10; Frizzled cysteine-rich domain; 2.
DR Gene3D; 3.30.70.960; SEA domain; 1.
DR InterPro; IPR015526; Frizzled/SFRP.
DR InterPro; IPR020067; Frizzled_dom.
DR InterPro; IPR036790; Frizzled_dom_sf.
DR InterPro; IPR000082; SEA_dom.
DR InterPro; IPR036364; SEA_dom_sf.
DR PANTHER; PTHR11309; FRIZZLED; 1.
DR PANTHER; PTHR11309:SF148; SECRETED FRIZZLED-RELATED PROTEIN 1; 1.
DR Pfam; PF01392; Fz; 2.
DR Pfam; PF01390; SEA; 1.
DR SMART; SM00063; FRI; 1.
DR SUPFAM; SSF63501; Frizzled cysteine-rich domain; 2.
DR SUPFAM; SSF82671; SEA domain; 1.
DR PROSITE; PS50038; FZ; 2.
DR PROSITE; PS50024; SEA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00090}; Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 63..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 90..214
FT /note="SEA"
FT /evidence="ECO:0000259|PROSITE:PS50024"
FT DOMAIN 325..411
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT DOMAIN 463..549
FT /note="FZ"
FT /evidence="ECO:0000259|PROSITE:PS50038"
FT REGION 205..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 330..391
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 338..384
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 468..529
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT DISULFID 476..522
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00090"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KOF80971.1"
FT NON_TER 581
FT /evidence="ECO:0000313|EMBL:KOF80971.1"
SQ SEQUENCE 581 AA; 63900 MW; 07D7A45C75DBFE68 CRC64;
EELSDPSIRG EGRKLKKLDH AYDNNGFAEY SEISHKDIGS HPKVNPSPKD EDMLRNGCSR
STYVPLLVLF LVSVIATAAA LAVIMTDKDE EKPKFFGYTV LNQTWKATYF NHSTADYHQL
VQEFTMKMDL LFKNSSFAAD YNRTEILTVR PGSVIILYRI ILNTITKQFN NLLTLIQKFF
PDSDISIDGQ FTTLSTNYPT TPVVPTTTTT TTTEMPTTKS TTTEVPTTTT KSTTTSTTEV
PTTTSTTEVP TTTTTTEVPT TTSTTEVPTT TTTTEVPTTT TTTEVPTTTI TTEVPTTSIT
TKEVPTTKTT TTEVPTTTTT SKLTTTTDNC FPLKFQKCLD AGYSRTMFPN FKDETAEEAI
ISFNTSALPI INSGCSPLSL HYMCGLLFPK CENGQAKFSC KSTCLAIEKN CGKNATLLPC
EHLTDDEMYC FLPEPHTTAS SSIRPSSVRH QTTATDVTWT TTQTNDNCFP LKFQKCLDAG
YSRTMFPNIK DETAEEAIIS FNTSALPIIN SGCSSLSLHY MCGLLFPKCE NGQAKFSCKS
TCLAIEKNCG KNATLLPCEH LTDDEMYCFL PEPHTTASST S
//
