ID   A0A0L8H9G9_OCTBM        Unreviewed;      1045 AA.
AC   A0A0L8H9G9;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   RecName: Full=Eukaryotic translation initiation factor 5B {ECO:0000256|ARBA:ARBA00013824};
DE   AltName: Full=Translation initiation factor IF-2 {ECO:0000256|ARBA:ARBA00032478};
GN   ORFNames=OCBIM_22019495mg {ECO:0000313|EMBL:KOF85943.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF85943.1};
RN   [1] {ECO:0000313|EMBL:KOF85943.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF85943.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF85943.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. IF-2 subfamily.
CC       {ECO:0000256|ARBA:ARBA00007733}.
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DR   EMBL; KQ418776; KOF85943.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L8H9G9; -.
DR   STRING; 37653.A0A0L8H9G9; -.
DR   EnsemblMetazoa; Ocbimv22019495m; Ocbimv22019495m.p; Ocbimv22019495m.g.
DR   EnsemblMetazoa; XM_014918790.1; XP_014774276.1; LOC106871994.
DR   OMA; EFAVMLC; -.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR   CDD; cd03703; aeIF5B_II; 1.
DR   CDD; cd16266; IF2_aeIF5B_IV; 1.
DR   CDD; cd01887; IF2_eIF5B; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 2.40.30.10; Translation factors; 2.
DR   Gene3D; 3.40.50.10050; Translation initiation factor IF- 2, domain 3; 1.
DR   InterPro; IPR029459; EFTU-type.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; T_Tr_GTP-bd_dom.
DR   InterPro; IPR015760; TIF_IF2.
DR   InterPro; IPR023115; TIF_IF2_dom3.
DR   InterPro; IPR036925; TIF_IF2_dom3_sf.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   NCBIfam; TIGR00231; small_GTP; 1.
DR   PANTHER; PTHR43381:SF4; EUKARYOTIC TRANSLATION INITIATION FACTOR 5B; 1.
DR   PANTHER; PTHR43381; TRANSLATION INITIATION FACTOR IF-2-RELATED; 1.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF14578; GTP_EFTU_D4; 1.
DR   Pfam; PF11987; IF-2; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF52156; Initiation factor IF2/eIF5b, domain 3; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF50447; Translation proteins; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Initiation factor {ECO:0000256|ARBA:ARBA00022540};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917}.
FT   DOMAIN          456..671
FT                   /note="Tr-type G"
FT                   /evidence="ECO:0000259|PROSITE:PS51722"
FT   REGION          1..46
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          59..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..18
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        73..313
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        328..388
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        410..425
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1045 AA;  119287 MW;  FB797FEC43C43AC2 CRC64;
     MLDDDSNSDR KDSDDETNDI VLETVTQSKQ SKKVKDKKKK KGKLEQEYDD IDAILADIEK
     VSEKKQPKSK KDKKKSSAST EANVSEVKKS EEVKKSEEVK KSEEVKKSEE VKKSEEVKKN
     EEVKKNEEVK DEVNEDLKLK AAAQKKKEKK EREKLKKQQD KQKDSDMQDK EKIIETQPKV
     VETPAEHHVD TKPEDDDETS RGGSAEPETN NKKKKKVKKE EVVEKPKKPK GQIAKIKEAL
     EKMKEEEERL RREEEEKERM LAEIQRKKEE QKLIEEERKR RKKQKEKEKK EQLKAEGKLL
     TEKQKHERMR AQQMLDAMRS QGLELPVKDE SAPKKRIVYT DKKKKRTQND ADSKREDSIV
     SDETKTDEKS IVTEMKPVEM KEEVKESWDI SSDEEESETD TKTKFDEDDS SDEKGDDDDS
     LKDDSDIEDY TPIEKARERI LKRKEAAEKK RRVDVLRAPV VCVLGHVDTG KTKILDKLRR
     TNVQDGEAGG ITQQIGATNV PHDALKEATK MVKEKPPLKL PGLLIIDTPG HESFSNLRSR
     GSSLCDIAIL VVDIMHGLEP QTIESINLLK ARKTPFVIAL NKIDRLFQWK TSPQTDVSVT
     IKKQNTNTKV EFEERSKESI LQISEQGLNA ALFYENTNVR EYINVVPTSA HTGDGMGNLI
     ATICELTQSL LAKRISYSEE LHATVMEVKA LPGMGTTIDV ILVNGKLKEG DTIVVAGTEG
     PIMTQIRGLL TPEPMKELRV KAQYQHHKEL MAAQGVKIMA KDLEKALAGL PLYVAKDQDE
     IDYYKSEVSN ALKEVLSGIK LQERGVFVQA STLGSMEALL EFLRTSKIPY AGINIGPIHK
     KDIMKASVML EHDDQYAVIL AFDVKIERDA QELADTLGVR IFSADIIYHL FDKFMTYREE
     LKKKRQGEFR HIAVFPCKLR VMPEYIFNSR DPIVVGVCVE AGFVKEGTPL CVPSKEFVEI
     GRVSGIENNH KQVEVAKKGQ EVCIKIEPIP GEAPKMFGRH FDHTDMIMSK ISRQSIDVVK
     DYFRDEMTKN DWQLIVELKK LFQII
//