ID   A0A0L8HNE3_OCTBM        Unreviewed;       209 AA.
AC   A0A0L8HNE3;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
DE   Flags: Fragment;
GN   ORFNames=OCBIM_22010702mg {ECO:0000313|EMBL:KOF90692.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF90692.1};
RN   [1] {ECO:0000313|EMBL:KOF90692.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF90692.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF90692.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KQ417704; KOF90692.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0L8HNE3; -.
DR   STRING; 37653.A0A0L8HNE3; -.
DR   EnsemblMetazoa; Ocbimv22010702m; Ocbimv22010702m.p; Ocbimv22010702m.g.
DR   EnsemblMetazoa; XM_014915392.1; XP_014770878.1; LOC106869589.
DR   OMA; ECIHTER; -.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   GO; GO:0002224; P:toll-like receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR017241; Toll-like_receptor.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR24365:SF541; MSTPROX-RELATED; 1.
DR   PANTHER; PTHR24365; TOLL-LIKE RECEPTOR; 1.
DR   Pfam; PF01582; TIR; 1.
DR   PRINTS; PR01537; INTRLKN1R1F.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        16..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          67..206
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KOF90692.1"
SQ   SEQUENCE   209 AA;  24588 MW;  44D0FA71D274BC93 CRC64;
     RLPLIITYLN HSCSSFIGII ITVACLIVLL GCFSFGALVY HFRWKLRYLY YMIRERYAYQ
     RIQTGEYLYD AFVSYAEEDR GCVFEYLIPE LEEKDTFKLN IHHRDFPAGK QIAENILSAI
     QSSRTCLILL SRSFLSSEWC MFEYNMAKME CIHTERDLVI VIMLEELSVD ILPLQLQHQI
     KTQSYICFPT ENATSDVFWN NLKKSIRDG
//