ID A0A0L8I689_OCTBM Unreviewed; 472 AA.
AC A0A0L8I689;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=OCBIM_22032884mg {ECO:0000313|EMBL:KOF96904.1};
OS Octopus bimaculoides (California two-spotted octopus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF96904.1};
RN [1] {ECO:0000313|EMBL:KOF96904.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF96904.1};
RC TISSUE=Gonad {ECO:0000313|EMBL:KOF96904.1};
RA Tran T., Druce J.;
RT "MeaNS - Measles Nucleotide Surveillance Program.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KQ416456; KOF96904.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0L8I689; -.
DR EnsemblMetazoa; Ocbimv22032884m; Ocbimv22032884m.p; Ocbimv22032884m.g.
DR EnsemblMetazoa; XM_014935046.1; XP_014790532.1; LOC106883908.
DR OMA; YIGINNP; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 1.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.20.5.300; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR InterPro; IPR032406; CLZ_dom.
DR InterPro; IPR018488; cNMP-bd_CS.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF16526; CLZ; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS00888; CNMP_BINDING_1; 1.
DR PROSITE; PS00889; CNMP_BINDING_2; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 89..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 265..383
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 472 AA; 54661 MW; 0AF8DF122D492639 CRC64;
MGVRLKTGYL EHGLMVRDTK KLRLNYLRSK SFRFDVASIL PTDLFYIITG INVPELRFNR
LLRFTRLWEF FDRTETRTNF TNLFRICKLV LYILVIIHWN ACAYFAISHS IGYGADGWVY
PNISEKKFAP LTRKYIYSFY WSTLTLTTIG ETPVPERDEE YLFVVVDFLI GVLIFATIVG
NVGNMITNMN AQRAEFQQRM DGVKQYMEFR KVSKELEQRV IKWFDYLWTN KQSLNEEEVL
SALPDKLKAE MAIHVHLDTL KQVRIFQDCE PGLLVELVLK LKLQVFSPGD YICRKGDIGR
EMYIVKRGQL QVVADDGITV YATLTDGSVF GEVSILNIAG NKTGNRRTAN VRSIGYSDLF
CLSKNDLWDA LTEYPAAKKQ LIERGRQLLL KDNLLDEEVL KKQEENEEST SQVVTRLETS
LDTLQTRFAR LLCDFNTTQQ KLKQRITKLE KVLARDDDSV SKVSDQSNNT ET
//
