ID   A0A0L8IAJ9_OCTBM        Unreviewed;       574 AA.
AC   A0A0L8IAJ9;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   RecName: Full=Cytokine-like nuclear factor N-PAC {ECO:0000256|ARBA:ARBA00034140};
DE   AltName: Full=Glyoxylate reductase 1 homolog {ECO:0000256|ARBA:ARBA00030287};
GN   ORFNames=OCBIM_22024901mg {ECO:0000313|EMBL:KOF98533.1};
OS   Octopus bimaculoides (California two-spotted octopus).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Cephalopoda;
OC   Coleoidea; Octopodiformes; Octopoda; Incirrata; Octopodidae; Octopus.
OX   NCBI_TaxID=37653 {ECO:0000313|EMBL:KOF98533.1};
RN   [1] {ECO:0000313|EMBL:KOF98533.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=UCB-OBI-ISO-001 {ECO:0000313|EMBL:KOF98533.1};
RC   TISSUE=Gonad {ECO:0000313|EMBL:KOF98533.1};
RA   Tran T., Druce J.;
RT   "MeaNS - Measles Nucleotide Surveillance Program.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC   -!- SIMILARITY: Belongs to the HIBADH-related family. NP60 subfamily.
CC       {ECO:0000256|ARBA:ARBA00007598}.
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DR   EMBL; KQ416131; KOF98533.1; -; Genomic_DNA.
DR   RefSeq; XP_014781204.1; XM_014925718.1.
DR   AlphaFoldDB; A0A0L8IAJ9; -.
DR   EnsemblMetazoa; Ocbimv22024900m; Ocbimv22024900m.p; Ocbimv22024901m.g.
DR   EnsemblMetazoa; XM_014925718.1; XP_014781204.1; LOC106876941.
DR   GeneID; 106876941; -.
DR   OrthoDB; 103196at2759; -.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd05836; PWWP_GLYR1; 1.
DR   Gene3D; 2.30.30.140; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR035501; GLYR1_PWWP.
DR   InterPro; IPR029154; HIBADH-like_NADP-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR000313; PWWP_dom.
DR   PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   Pfam; PF14833; NAD_binding_11; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   Pfam; PF00855; PWWP; 1.
DR   SMART; SM00293; PWWP; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR   PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
DR   PROSITE; PS50812; PWWP; 1.
PE   3: Inferred from homology;
KW   Chromosome {ECO:0000256|ARBA:ARBA00022454}.
FT   DOMAIN          7..66
FT                   /note="PWWP"
FT                   /evidence="ECO:0000259|PROSITE:PS50812"
FT   REGION          118..241
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        122..140
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..181
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..196
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..241
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   574 AA;  63432 MW;  E9A4918722867229 CRC64;
     MASKFKVGDL VWAKMKGFCA WPAKIIEPMS EVKRPTSKKT HHFVFFFGSE NYAWVQEDSI
     YNYQDNKSKY TLTSRIPRGY NVAIEAIEDV IKAMPSQIAK KKILSNSIKK YVPLASNGKD
     SSKVDKVLHR DKHESSAAQF KKKSVARLNI RNSRSDNIRL QTKEKSKSPE KETKDESSPL
     KSSLKRLSSS NYAPKNKKSK MVVRVAAPQT KTDIPSRKSV SKKANLSLNR KNSPLKPKAH
     QNSIKLTENN VYESTQLPVK SVSSATQIEE TLLSRSISSV NTNVYPTKLK IGFLGLGIMG
     QGMVMNLIRS GHEVTVWNRT STKCRDFIKE GALKKNTPAD VVHACDITIS CISDTAAVKD
     VVFGNCGVIQ GISSGKGYVE MSTIDEETIK DVREAVVLRG GRFLEAPVCG SRVPALEGQL
     VILASGDRKL YEDCHSSFEA MGKRSFFLGE TGMATRMKLV VNMMLGSMMA SLAETMALAQ
     KAGLEQEDVA TILSLGPLAS TTVCYKSQAI MNNKHDPHFP LQHQQKDLRL ALDLGDRVEQ
     PLYVAAAANE LYKKARRLGY GESDISAVYR ATSA
//