ID A0A0M0JP76_9EUKA Unreviewed; 691 AA.
AC A0A0M0JP76;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Subtilisin {ECO:0008006|Google:ProtNLM};
GN ORFNames=Ctob_003037 {ECO:0000313|EMBL:KOO28092.1};
OS Chrysochromulina tobinii.
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Prymnesiales;
OC Chrysochromulinaceae; Chrysochromulina.
OX NCBI_TaxID=1460289 {ECO:0000313|EMBL:KOO28092.1, ECO:0000313|Proteomes:UP000037460};
RN [1] {ECO:0000313|Proteomes:UP000037460}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP291 {ECO:0000313|Proteomes:UP000037460};
RX PubMed=26397803; DOI=10.1371/journal.pgen.1005469;
RA Hovde B.T., Deodato C.R., Hunsperger H.M., Ryken S.A., Yost W., Jha R.K.,
RA Patterson J., Monnat R.J. Jr., Barlow S.B., Starkenburg S.R.,
RA Cattolico R.A.;
RT "Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin:
RT Metabolic Tools for Enhanced Algal Fitness in the Prominent Order
RT Prymnesiales (Haptophyceae).";
RL PLoS Genet. 11:e1005469-e1005469(2015).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOO28092.1}.
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DR EMBL; JWZX01002622; KOO28092.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M0JP76; -.
DR OrthoDB; 5474719at2759; -.
DR Proteomes; UP000037460; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR002884; P_dom.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR PANTHER; PTHR42884:SF14; NEUROENDOCRINE CONVERTASE 1; 1.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR Pfam; PF01483; P_proprotein; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51829; P_HOMO_B; 1.
DR PROSITE; PS50106; PDZ; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000037460};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 284..432
FT /note="P/Homo B"
FT /evidence="ECO:0000259|PROSITE:PS51829"
FT DOMAIN 568..623
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 512..535
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 661..691
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 512..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 661..679
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 691 AA; 74161 MW; 00CFCD3DEDC27E4B CRC64;
MDRNHISSNS WGIDPCTALA SSGRRKLRQR LLQGCPFAAT AASGTSPCSD SQCAGASWTS
PPSTCEAVIS TYCQDSYNYV ADGECALWTY LWMTCAYTHL HWDTVRVLQR GVLEGRSRRG
IVYVFSSGNE YTHGEDVNME QYLHSRFTIT VGATDKLGLH AYYSTTGSSL FITAPGGDSH
QHSNSWYMAA AGGGCAALVE GSYLQGTSFA CPVVSGVVAL MLEANPLLGW RDVQGILAAT
TSRNDPTSPL WTTNAAGFIH NIKYGFGMVD ASAAVAAALS WTNWGIEQRI IASSTQHLLT
VPHDGSTLST SVTVSAQSQT WAIEWIEIFL NLDHSSRGDL QLELTSPSGT HSILTPGPRP
ETSNPPVEGC SAAADTCEFN NDGTCDNPEY CECDYVDCLA ANWVGENGQP SLYMPRFNWK
MTSVRSWGES PATLLLALCA IQNVCVEIEY VDKLKAAGGM ERLQHIVGLA DPQLCQFAQG
CFDNVRTVVA INAMQHMQQN FLRTRPKAEK AAAEAEAAEE SAAEKAAAEK AATGGAEPVL
AKPTAYRRQR SLRQKIRSSV VVETCIQTCI IVKEDQGSIG LDLQQSSGHR ISIVRVKPDT
PAARSVPPLV AGMAIVSVNG FPVLDAKVAA ECIAKAGRGQ MMLEVAPEAT RSWLSRLRRA
SARQESVKGA DEARMSGDED SGHGAALAAE P
//
