ID A0A0M0LRM3_9EUKA Unreviewed; 3007 AA.
AC A0A0M0LRM3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Flagellar outer dynein arm heavy chain beta {ECO:0000313|EMBL:KOO53710.1};
DE Flags: Fragment;
GN ORFNames=Ctob_010606 {ECO:0000313|EMBL:KOO53710.1};
OS Chrysochromulina tobinii.
OC Eukaryota; Haptista; Haptophyta; Prymnesiophyceae; Prymnesiales;
OC Chrysochromulinaceae; Chrysochromulina.
OX NCBI_TaxID=1460289 {ECO:0000313|EMBL:KOO53710.1, ECO:0000313|Proteomes:UP000037460};
RN [1] {ECO:0000313|Proteomes:UP000037460}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=CCMP291 {ECO:0000313|Proteomes:UP000037460};
RX PubMed=26397803; DOI=10.1371/journal.pgen.1005469;
RA Hovde B.T., Deodato C.R., Hunsperger H.M., Ryken S.A., Yost W., Jha R.K.,
RA Patterson J., Monnat R.J. Jr., Barlow S.B., Starkenburg S.R.,
RA Cattolico R.A.;
RT "Genome Sequence and Transcriptome Analyses of Chrysochromulina tobin:
RT Metabolic Tools for Enhanced Algal Fitness in the Prominent Order
RT Prymnesiales (Haptophyceae).";
RL PLoS Genet. 11:e1005469-e1005469(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOO53710.1}.
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DR EMBL; JWZX01000104; KOO53710.1; -; Genomic_DNA.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000037460; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF36; DYNEIN HEAVY CHAIN AT 93AB, ISOFORM C; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell projection {ECO:0000313|EMBL:KOO53710.1};
KW Cilium {ECO:0000313|EMBL:KOO53710.1};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Flagellum {ECO:0000313|EMBL:KOO53710.1};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000037460}.
FT DOMAIN 189..767
FT /note="Dynein heavy chain tail"
FT /evidence="ECO:0000259|Pfam:PF08385"
FT DOMAIN 1281..1679
FT /note="Dynein heavy chain linker"
FT /evidence="ECO:0000259|Pfam:PF08393"
FT DOMAIN 1825..2160
FT /note="Dynein heavy chain hydrolytic ATP-binding dynein
FT motor region"
FT /evidence="ECO:0000259|Pfam:PF12774"
FT DOMAIN 2324..2441
FT /note="Dynein heavy chain AAA 5 extension"
FT /evidence="ECO:0000259|Pfam:PF17852"
FT DOMAIN 2667..2762
FT /note="Dynein heavy chain 3 AAA+ lid"
FT /evidence="ECO:0000259|Pfam:PF17857"
FT DOMAIN 2814..3007
FT /note="Dynein heavy chain AAA module D4"
FT /evidence="ECO:0000259|Pfam:PF12780"
FT NON_TER 3007
FT /evidence="ECO:0000313|EMBL:KOO53710.1"
SQ SEQUENCE 3007 AA; 341898 MW; A32B3678EBEA84CB CRC64;
MGDAPTDKRI DFLRDRIVQL LKCKPELFDA LLKTEEGELI KRFLNDGGCT RIFFSAGPKD
MFVTEKLPDD KQTKKKAIFA MKLAEDVKFD EKKMDEMFDL CMVGDLSPAM LNNLYNTLRS
VYLPIITNPG FINAKPGVVM KQFIDKYNWM LAAVHTAVGQ TQGKTALWLP PVEAPSAGSS
KDRSDKDRVH VLESAIVMWT ERINTSLNRD PDSVFGAVGT KDELFPGPIV GIDFWQGKCI
DLGDILEQLS SPHIVKVMKV LEIIRSPYHA SFKALMNQLS IRHAEAKDNV KFLDSLRPKF
TALLQSDFTE IAMHFKPTMH TLLMIWKHSK FYNTPPALAL MVRMLCNDVI EKAHEFLGGT
GELFGAEPKE SVEKINRVLN VCRALKSDYY MYYALSKTQC EHNPWMADRG NMFKRLDLFI
TRCEDLLHLC RTAQQFEKLI TVVIGGIAGA ALTQDSETIA KEFDKALNKM KELTYDVLDV
QITKFEEDIT RFSVSVKELE TRVAKVLGLG FEECDTISKG FKLVDSFGDL LERDFVQADL
EAKQLELIRI YAEELKQVQE LFTRDRTGSA SKAKFFERDG PPLYINMPPV SGALAWVQGL
RRRLEEPMRS LMPVLRIMED TDEVKDVKRM FDSIIKVLRE YEDMMFDAWQ GGVDTTLGEK
LTLPLITRDP KSQEIEVNFD LQLTKLLSEC KYFVMQKKKI PDVAQQLFDG AETFRVHTAN
LTLVKNKYNE MLRIMLDVEK PLLKGSMKAI DKVLDRGLKV LVWKSPNPEK DAFITEALGL
VEEAYKMLHE IKKNMNKVNE ILAGWVSLPF MTRLSINKTY NPSAYMEEHS RFLETRTKDI
TEGIKKIHEY VKESNECLKV SKGAPAWRAY VEFMNNILIN GVADTVVASL GYLLAQLDPK
IIAKLEKAPF FDIKLDLNVV AKGDDAVFFA PPLDGKEPSV TSYVTALIAD FYNIVKGLKR
LDRTEGDFLK EMEENEMVRF NVHRIVDELE ANQTAARELR APFLKHRALW AKDIAHTLEV
FLDEATVAAD ENNPQIRMPN LAVFEARITE LREEEAEIKA LQNVINEGWL RIDAKPTKMT
LTTLAAKWID AYTSYLKNHV LSELDGLGQF IGLIKETLTS EALPSEGDRK GLFDAMARVR
DVRNREDRTN NLFVPLKDTI QLLKKFGVAM PEGTTDTLEM IPFSWEDTKK ITLNARENLG
PLQAQEQDRV REETEVFRGE VSAFTKRFHD EAPFEFKVGC DAAYVSINKF AKELMTFEKR
AVDIARNQEL FELAVTNWRD LKTIRTELTL LKLSWDFVQY VQDIFGSFRA TLWTAVDVEA
MSDQTKKLQK EVKTLNKAIH KWDVHIGLMA LVASMSISLE VVAELRDDAM RERHWKQLMV
VCKQTFIMDD KLQLDALLKL ELDKFRDPVG EIVERARAEI KIDLQLQKII KTWSGLFLFY
KPYKTSGVQV LEQPGDVFEA LDDNEVVLQN MMGNRFVGFF ETTVTSWKAK LAATRSTLDV
WLEVSRSWMQ LESIFLASED IREQLPEDAK RFDAIDAAFR EQMADACQNN NPIEVCMASG
REEVFKKNFE MLELCQKSLG DYLEVKKKKF PRFYFISGAD LVDILSKGRY APNVQPHFSK
FTDATGFIDW APDADGKLTG LARGCIAIDG EKFPYPEPKM CEGAVEDWLL ELMKHQAAMF
RIKVKESLDA YLDNPREKWI DMYGSQHCIQ TGQVWWTAEV HAAYDRLEQG NENAMKEYLE
LCRTGLKNYA AMVLGEMTGE LRTKVKTLIT IDTHAREIVE KLVIIKSETP TDFTWASQLK
FRWPDADGPQ DLYINICDAE FASRHEYVGN PGRLVITALT DRCYITLTQA LRLMMGGAPQ
GPAGTGKTET TKDLGRGLSI WVIVSNCSDQ MNNKVTGSFF SGLAQTGAWG CFDEFNRITV
EVLSVVATQY GSILQGIRAN KTRFMFEEEE INLVNSIGAW ITMNPGYAGR AELPENLKAL
FRPCAMVTPN FENIAEINLA GEGFVESKDL ANKFVTMYYV CGQLLSKQMH YDWGLRAMSG
VLRIAGGMKR ADPDKSEKQI LMRAMRDTNL PKFVQADFGI FQKVITDLYP GIDCPAIINP
ALKQAIQDVI KDPETHWWGT LGRPVLQAEE NFVIKTINLF EALSVRHCVF VLGTAGAAKS
ELWKTLAAAQ SFMKIGGGNT LYNPLNPKAV TSNELYGYVH PVTKENFDGV IAKIMRDFAS
VPPDHKNVNV PKWMVLDGDI DAEWIESMNT VMDDNRILTL TTNERIPLTK SMKLILEISH
LRNASPATAS RAGCVFLNET DVGWRPYVAM WVETMGDAKT QTILEQLFET MVAPTLSMIR
KEKWEHVTPV KDLAIVEVIC RILEAVLTPE TCPAGSEKEV YESFFQFAAV WGIGGAFGSD
KGADFRKALD GYWRTEFGKL SMRFPDEGSI FDYFIDPTTK KNEPKRCTHW REIVPGYTHD
RAESYSRIFV PTLDTTRLLW FSNNMLKLRK PIMFVGNSGS AKTVVANVLL RQQDEEVWMY
NIISFNSFTI AASLQVMLEA PLEKKTGTIF GPPGVKKLIY FIDDFNMPSP DKYGNQSSIS
LLNQLKDYGG FYDLKGLRMK RVDNTLVVAA MNPFSGTFYV QDRMQRHFCT LSTPFPSQEV
LTHIYKNIMG GHFEIFNDGI RDALPMLLNF AVALHNQVAD NFVPSAVKFH YQWNLRAMAS
VFQGLYITSP ANYKDPVRMA RLLIHEAYRV YSDRMVIESD CEKFQELVTK NVKAHLAALD
QEALNEWPIQ LFSTFVEEAE GEQKMYLPIE GGYEQLSKLL TKQLAMYNES FAIMNLVLFN
QAMEHIARIS RIIDNPRGNG LLVGVGGSGK QSLTRLAAFI GGCEIFSIKL TSSYNVVDFK
EDLRNIYLKT GVKAIPTVFL FTDQQIFHEN ALIFINDILS LGYPAGLFAE EDRDTICNGV
RNDAKQAGYM DAKEQLWEFF INRVRALLHI CLCMSPVGDK MRNRCRKFPA LTSCTTCDWF
FNWPQQA
//
