ID   A0A0M2GXS0_9ACTN        Unreviewed;       303 AA.
AC   A0A0M2GXS0;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Dehydrogenase {ECO:0000313|EMBL:KJK40458.1};
GN   ORFNames=UK15_08690 {ECO:0000313|EMBL:KJK40458.1};
OS   Streptomyces variegatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=284040 {ECO:0000313|EMBL:KJK40458.1, ECO:0000313|Proteomes:UP000034786};
RN   [1] {ECO:0000313|Proteomes:UP000034786}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL B-16380 {ECO:0000313|Proteomes:UP000034786};
RA   Ju K.-S., Doroghazi J.R., Metcalf W.;
RL   Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HIBADH-related family.
CC       {ECO:0000256|ARBA:ARBA00009080}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJK40458.1}.
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DR   EMBL; JYJH01000004; KJK40458.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M2GXS0; -.
DR   STRING; 284040.UK15_08690; -.
DR   PATRIC; fig|284040.3.peg.5033; -.
DR   Proteomes; UP000034786; Unassembled WGS sequence.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR048666; RedAm-like_C.
DR   PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   Pfam; PF21761; RedAm-like_C; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
FT   DOMAIN          18..173
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          176..301
FT                   /note="NADPH-dependent reductive aminase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21761"
SQ   SEQUENCE   303 AA;  30997 MW;  128E3BA70990B3CE CRC64;
     MAPAHSGRPS ADHPSATVTV LGLGPMGRAL AGAFVDAGLR TTVWNRTPGR DRELLDRGAA
     GAASAAEAVA ASEVTVVCVV NYDAADAVLR QEEVAAALKG RTVVNLTADT PARARDTAGW
     ATAHGVRYLD GAIMTPTTTI GTPDAVFLYS GPDDLYHELA PVRQALGGTH THLGEDAGRA
     AAYDIALLDI FWTAMSGYAH ALAVARAEGV TATELAPFAQ GIGAILPPLF AGTAADADAG
     TYSGEGNPLT SAVSSMSHIV HVSESHGIDA GVMRAAEGMA RRTIGLGHGQ DGFIRVAEVI
     GRR
//