ID A0A0M2JYR9_9MYCO Unreviewed; 977 AA.
AC A0A0M2JYR9;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Cyclic di-GMP phosphodiesterase Gmr {ECO:0008006|Google:ProtNLM};
GN ORFNames=WN67_20515 {ECO:0000313|EMBL:KKF00093.1};
OS Mycolicibacterium obuense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1807 {ECO:0000313|EMBL:KKF00093.1, ECO:0000313|Proteomes:UP000034150};
RN [1] {ECO:0000313|EMBL:KKF00093.1, ECO:0000313|Proteomes:UP000034150}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UC1 {ECO:0000313|EMBL:KKF00093.1,
RC ECO:0000313|Proteomes:UP000034150};
RA Greninger A.L., Cunningham G., Chiu C.Y., Miller S.;
RT "Genome sequence of Mycobacterium obuense UC1.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF00093.1}.
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DR EMBL; LAUZ02000081; KKF00093.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2JYR9; -.
DR STRING; 1807.MOBUDSM44075_04957; -.
DR PATRIC; fig|1807.13.peg.4999; -.
DR OrthoDB; 23692at2; -.
DR Proteomes; UP000034150; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR007895; MASE1.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF11; DIGUANYLATE CYCLASE DGCE-RELATED; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF05231; MASE1; 1.
DR Pfam; PF08448; PAS_4; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 37..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 61..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..106
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 152..171
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 192..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 409..463
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 492..544
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 577..711
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 721..974
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 977 AA; 105144 MW; 540C889F86AAFB4B CRC64;
MVVDRRWVAY FVAFPIAYTL AIVAGRATRL GGDEISLVWP AAAVATVWLL ATRDCPLQRR
LAHVALLLVL TFAVNLTTGA SVPLALWFVV VNGLLAAVTA AVLTRGGRAP TLRDPADLAH
LVVAVVVGTS TAAVLAAGYF WVVERDGFGE NFALFAVRNG ASTLLGVSVW LRAREITPRR
PRITTRGLAE ALAATATAVV AFVYAFWLNT GVPIAFIVLV PAVWLALRYS TMVSTTFLLV
AGAWIVGATL RERGALIVPD VEMRALLAQA MVCSLTIVVL TLALYRDSRA RLIDQLSSAR
DSAARTSELL GAVLDSIHDS VLLTDADGVA VLQNAQATSS GCVDDVVRAA NETSSSGVSG
AQRRDLELPE QDRVVELTTT PLTRQSAFTV AAFRDVTEER RHAEQLRAAH DLFAGVLQAA
SEQAIIGTDA NGLITVFNNG AERLLGWSAD EMIGRTPIEF HDPLEVRARA AELGISPAFH
VFVHDVTPHN ADVREWTYVR RDGNRVAVSL AVSQMTDHDG TCVGYIGVAT DITERKAFEA
ELQHLATHDP LTGLANRALF MNSLEAALAG AHQVGSRGVG LIFLDLDGFK AVNDTLGHAQ
GDEVLKIVAR RLQSVIAADC IAARLGGDEF AVLCTDVGAA DDLHHAAERI RAELRRPVRL
GMGRMYDRLS VSVGMVLSEP GCGGETLLQR ADSLMYSAKR NGKDCVATGG DALRATVRRH
EVQLRSEISR ALDRDEFTVH YQPIVALETT KTVAAEALLR WEHPRRGLLL PGEFLTVAEA
SAFMPAIGRR VLNEACRNAA SWIAPWSASA VHVNVSGRQL ERGDLRGDVV GALEMTGLDP
RRLVLELTET HAGGIAGSTP DDLEWLRGLG VRIAIDDVGT GFNGLQKMVD LPVDIIKISR
EFIAGMLDDD RCATFTRAIV DLGPRVGMTV IAEGIERPEQ RDRLVEWGCT LGQGFLFGHA
RSDLDGIKSP VVLFDPA
//
