ID A0A0M2K7W5_9GAMM Unreviewed; 369 AA.
AC A0A0M2K7W5;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=EmrA {ECO:0000313|EMBL:KKF35019.1};
GN ORFNames=SY86_05600 {ECO:0000313|EMBL:KKF35019.1};
OS Erwinia tracheiphila.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=65700 {ECO:0000313|EMBL:KKF35019.1, ECO:0000313|Proteomes:UP000033924};
RN [1] {ECO:0000313|EMBL:KKF35019.1, ECO:0000313|Proteomes:UP000033924}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BuffGH {ECO:0000313|EMBL:KKF35019.1,
RC ECO:0000313|Proteomes:UP000033924};
RA Shapiro L.R.;
RT "Erwinia tracheiphila.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKF35019.1}.
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DR EMBL; JXNU01000003; KKF35019.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2K7W5; -.
DR STRING; 65700.SY86_05600; -.
DR PATRIC; fig|65700.7.peg.1411; -.
DR Proteomes; UP000033924; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 2.
DR InterPro; IPR043602; CusB_dom_1.
DR InterPro; IPR032317; HlyD_D23.
DR PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR PANTHER; PTHR30386:SF26; TRANSPORT PROTEIN COMB; 1.
DR Pfam; PF00529; CusB_dom_1; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 2.
PE 3: Inferred from homology;
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022519};
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000033924};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..366
FT /note="Cation efflux system protein CusB"
FT /evidence="ECO:0000259|Pfam:PF00529"
FT DOMAIN 66..314
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 138..235
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 369 AA; 40935 MW; 3CF4C869C6496CBF CRC64;
MDNQSTSHPD DKQQQQDNVE QPERQRPGKK PLVILAIVVV IVLIIALWFW LSTRNIESTD
DAFTDADAVT IAPKASGYVT QLLVRDNQRV EKGDLLVVID PRDAMAQRDQ AEAQLALVVS
QWHQAESQLS LSEVQYPAQK DQALAQQAKA EADFLNAQED YKRQRGVDPR ATSQRSIDAA
SARLRSAKAE LESAKARVEV ASQIALQIRQ QKTNVEARQA QVQQAQAQLN IANLNLSWME
VRAPYDGFVT RRNVQMGTLV QAGTSLFSLV SADTWITANF KESQLSRMKP GNKVEITIDA
WPDRKLHGHV DSIQMGSGSR FSTFPAENAT GNYVKIVQRV PVKIVIDEGL DPNRPLPLGL
SAEPEVAVE
//
