ID A0A0M2RCB0_9PROT Unreviewed; 328 AA.
AC A0A0M2RCB0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=2-hydroxyacid dehydrogenase {ECO:0000313|EMBL:KKJ77218.1};
GN ORFNames=WH95_09235 {ECO:0000313|EMBL:KKJ77218.1};
OS Kiloniella litopenaei.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Kiloniellaceae; Kiloniella.
OX NCBI_TaxID=1549748 {ECO:0000313|EMBL:KKJ77218.1, ECO:0000313|Proteomes:UP000034491};
RN [1] {ECO:0000313|EMBL:KKJ77218.1, ECO:0000313|Proteomes:UP000034491}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1-1 {ECO:0000313|EMBL:KKJ77218.1,
RC ECO:0000313|Proteomes:UP000034491};
RA Shao Z., Wang L., Li X.;
RT "Genome sequence of Kiloniella sp. P1-1, isolated from the gut microflora
RT of Pacific white shrimp, Penaeus vannamei.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC ECO:0000256|RuleBase:RU003719}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKJ77218.1}.
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DR EMBL; LANI01000005; KKJ77218.1; -; Genomic_DNA.
DR RefSeq; WP_046505909.1; NZ_LANI01000005.1.
DR AlphaFoldDB; A0A0M2RCB0; -.
DR STRING; 1549748.WH95_09235; -.
DR PATRIC; fig|1549748.8.peg.3871; -.
DR OrthoDB; 9793626at2; -.
DR Proteomes; UP000034491; Unassembled WGS sequence.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05301; GDH; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR10996:SF178; 2-HYDROXYACID DEHYDROGENASE YGL185C-RELATED; 1.
DR PANTHER; PTHR10996; 2-HYDROXYACID DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00389; 2-Hacid_dh; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|RuleBase:RU003719};
KW Reference proteome {ECO:0000313|Proteomes:UP000034491}.
FT DOMAIN 18..323
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase
FT catalytic"
FT /evidence="ECO:0000259|Pfam:PF00389"
FT DOMAIN 113..292
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 328 AA; 36334 MW; 2690ECFB438270A9 CRC64;
MTQKKPLVIV TRRLPDAIET RMMELFDCRL NLDDKPFSQK ELIAAVKEAD VLVPTVTDRV
DAGVLAQAGP NLRLIASFGT GVDHIDLKTC RQRGITVTNT PGVLTEDTAD MTMALILAVS
RRITEGVKLI KSGEWTGWSP TGMLGHRMWG KRLGIIGMGR IGQAVARRAK GFGLSIHYHN
RRKVHPDIEN ELEATYWESL DQMLSRMDVI SVNCPHTPAT FHLLSSRRLK LLNDRAIIVN
TSRGEVIDEN ALARLIKSRD IAGAGLDVFE QEPAVNPKLQ ASENVVLLPH MGSATIEGRH
DMGEKVIINI KTFVDGHTPP DRVVEAMF
//
