ID A0A0M2S3G0_9ACTN Unreviewed; 311 AA.
AC A0A0M2S3G0;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Dehydrogenase {ECO:0000313|EMBL:KKK07566.1};
GN ORFNames=LQ51_01655 {ECO:0000313|EMBL:KKK07566.1};
OS Micromonospora sp. HK10.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=1538294 {ECO:0000313|EMBL:KKK07566.1, ECO:0000313|Proteomes:UP000034330};
RN [1] {ECO:0000313|EMBL:KKK07566.1, ECO:0000313|Proteomes:UP000034330}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HK10 {ECO:0000313|EMBL:KKK07566.1,
RC ECO:0000313|Proteomes:UP000034330};
RA Talukdar M., Das D., Borah C., Deka Boruah H.P., Bora T.C., Singh A.K.;
RT "Draft genome sequence of Micromonospora HK10, isolated from Kaziranga
RT National park, Assam, India.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKK07566.1}.
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DR EMBL; JTGL01000012; KKK07566.1; -; Genomic_DNA.
DR RefSeq; WP_046563517.1; NZ_KQ058701.1.
DR AlphaFoldDB; A0A0M2S3G0; -.
DR STRING; 1538294.LQ51_01655; -.
DR PATRIC; fig|1538294.3.peg.1095; -.
DR HOGENOM; CLU_029393_5_0_11; -.
DR OrthoDB; 9766715at2; -.
DR Proteomes; UP000034330; Unassembled WGS sequence.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR11516:SF2; PYRUVATE DEHYDROGENASE ALPHA SUBUNIT-RELATED; 1.
DR PANTHER; PTHR11516; PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BACTERIAL AND ORGANELLAR; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 25..297
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 311 AA; 33765 MW; 4BD4A28A1D34491B CRC64;
MTAAVTAAPP APSRLADDDL DLLLLIRHFE LALLDMFGRG ELHGTTHTCL GQEYVPVALR
PLLADGDHVF SNHRGHGHYL ARFGDPHGLL AEVMGRQGAV CRGVGGSQHI LRDRYLSTGV
QGESVPVAAG VALHLRRAEP GHLALVHLGD GTWGEGAVYE GLNMAALWRL PLLLVVEHNG
IAQSTPTSAQ LAGDLAGRAR AFGVAHTLVT STDTNTVRAA LAPVLRRVRE RGTPAVVELR
THRVGPHSKG DDTRRPEEIG YARAQDWYAR YARAYPEQFA AHDERQRRHV AEVVREVAGR
PASRWEEAGR G
//
