ID A0A0M2U2C7_9FIRM Unreviewed; 536 AA.
AC A0A0M2U2C7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=HTH-type transcriptional regulatory protein TyrR {ECO:0000256|ARBA:ARBA00029500};
GN ORFNames=SY88_22015 {ECO:0000313|EMBL:KKM08787.1};
OS Clostridiales bacterium PH28_bin88.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1605376 {ECO:0000313|EMBL:KKM08787.1, ECO:0000313|Proteomes:UP000034222};
RN [1] {ECO:0000313|EMBL:KKM08787.1, ECO:0000313|Proteomes:UP000034222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Robbins S., Tyson G.;
RT "High quality genome sequence of Candidatus Suratobacter aromatica.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKM08787.1}.
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DR EMBL; LAKY01000072; KKM08787.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2U2C7; -.
DR STRING; 1605376.SY88_22015; -.
DR PATRIC; fig|1605376.3.peg.448; -.
DR Proteomes; UP000034222; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR030828; HTH_TypR.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR NCBIfam; TIGR04381; HTH_TypR; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR32071:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN TYRR; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF18024; HTH_50; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW Aromatic hydrocarbons catabolism {ECO:0000256|ARBA:ARBA00022797};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000034222};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 6..75
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
FT DOMAIN 81..135
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 148..200
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 209..439
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 536 AA; 59355 MW; 4177CC3FEC5685A6 CRC64;
MTEYLRVVIE AEDRVGMTLD ILRVIYDFQL NIVSMEVHPQ VVYVKLACTS PNRWEQLVDA
LTRVPGVDSV GQVEFLPSER REQQMKAVLN SVSEGIIAVD NKGEVTLINP AAERILQCPE
SKALGRPVQE VLSPDVPMLK ALADGKGYDH EEILINTPRG RSHYITTGRS MQDEKGRITG
VVAALKDMSQ VRDLVYSITR PSMITFDAII ARSQVMKNMI NLARTVAKSD STVLIRGESG
TGKELFARAL HMASPRKHKP FVPINCAALP DSLLESELFG YEEGAFTGAR KGGKQGLFEF
AHQGTVFLDE IGELSPHLQV KLLRVLQDGK VRRIGGKEEF PVNARVVTAT NRNLEEMLRQ
GTFREDLYYR LNVIPLFLPP LRERKEDIPF LVESFISKLN ARLGTSVKGI SPEATGKLMG
YAWPGNVREL ANAIERAINL AGNSEVLEPS HLIITSGEMY PYPLAAKDAR GKENSPAGNP
SQVLFLAEQV AETEAQALKQ ALAIYKSSRL AGKALGVSHT TVLKKMKRYR LNDLEA
//
