ID A0A0M2U826_9FIRM Unreviewed; 477 AA.
AC A0A0M2U826;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=4-hydroxybutyryl-CoA dehydratase {ECO:0000313|EMBL:KKM10421.1};
GN ORFNames=SY88_13880 {ECO:0000313|EMBL:KKM10421.1};
OS Clostridiales bacterium PH28_bin88.
OC Bacteria; Bacillota; Clostridia; Eubacteriales.
OX NCBI_TaxID=1605376 {ECO:0000313|EMBL:KKM10421.1, ECO:0000313|Proteomes:UP000034222};
RN [1] {ECO:0000313|EMBL:KKM10421.1, ECO:0000313|Proteomes:UP000034222}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Robbins S., Tyson G.;
RT "High quality genome sequence of Candidatus Suratobacter aromatica.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KKM10421.1}.
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DR EMBL; LAKY01000051; KKM10421.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M2U826; -.
DR STRING; 1605376.SY88_13880; -.
DR PATRIC; fig|1605376.3.peg.1716; -.
DR Proteomes; UP000034222; Unassembled WGS sequence.
DR GO; GO:0016627; F:oxidoreductase activity, acting on the CH-CH group of donors; IEA:InterPro.
DR Gene3D; 1.10.3140.10; 4-hydroxybutyryl-coa dehydratase, domain 1; 1.
DR Gene3D; 2.40.110.10; Butyryl-CoA Dehydrogenase, subunit A, domain 2; 1.
DR Gene3D; 1.20.140.10; Butyryl-CoA Dehydrogenase, subunit A, domain 3; 1.
DR InterPro; IPR046373; Acyl-CoA_Oxase/DH_mid-dom_sf.
DR InterPro; IPR036250; AcylCo_DH-like_C.
DR InterPro; IPR009100; AcylCoA_DH/oxidase_NM_dom_sf.
DR InterPro; IPR004925; HpaB/PvcC/4-BUDH.
DR InterPro; IPR024719; HpaB/PvcC/4-BUDH_C.
DR InterPro; IPR024674; HpaB/PvcC/4-BUDH_N.
DR PANTHER; PTHR36117; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR PANTHER; PTHR36117:SF3; 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED; 1.
DR Pfam; PF03241; HpaB; 1.
DR Pfam; PF11794; HpaB_N; 1.
DR PIRSF; PIRSF000331; HpaA_HpaB; 1.
DR SUPFAM; SSF47203; Acyl-CoA dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF56645; Acyl-CoA dehydrogenase NM domain-like; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|PIRSR:PIRSR000331-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000034222}.
FT DOMAIN 4..272
FT /note="HpaB/PvcC/4-BUDH N-terminal"
FT /evidence="ECO:0000259|Pfam:PF11794"
FT DOMAIN 280..474
FT /note="HpaB/PvcC/4-BUDH C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03241"
FT BINDING 189
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000331-2"
SQ SEQUENCE 477 AA; 53159 MW; B33D751C7958BA44 CRC64;
MKRGDEYVES LRTLRMKVYA FGERITNLVD DPLFRPHVNA ARMTYDLAYD PVGEDLVTAT
SHLTKKKINR FTHIHHSAGD LVRKVKMLRM IARRTGTCFQ RCVGFDGLNA LYSVTYEMDQ
ELGTEYHQRF VNYLLYVQEN DLMLAGSMTD PKGDRSLKPH QQADPDLYVH VVRQNEKGIW
LRGAKAHQTG IVNSHEMLVM PTTAMGEEDK DYAVACAIPV DAPGITHIFG RQTNDERKRG
EIDQGNALFG IVGGEALTVL EDVFVPWERV FMCGEYRFAG LLVERFASYH RQNYGGCKGG
VSDIIIGATT TMAEYNGVEK ASHIRDKIAE MIHLTESLYA GSIACSAEGY ATSSGAYFVD
PLLANVTKQN VTRFIYEICR LSHDVAGGLI ATLPSEQDLR HPEVGPYVDK YFRGAAGVSS
EDRIRIARLI ENMTGGTALA ESMHGAGSPQ AQRVMILRQA NLAHKKTWAR KLAGIKS
//
