ID   A0A0M2USW0_9BACT        Unreviewed;       910 AA.
AC   A0A0M2USW0;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   RecName: Full=nitrate reductase (quinone) {ECO:0000256|ARBA:ARBA00012500};
DE            EC=1.7.5.1 {ECO:0000256|ARBA:ARBA00012500};
GN   ORFNames=BROFUL_03229 {ECO:0000313|EMBL:KKO18081.1};
OS   Candidatus Brocadia fulgida.
OC   Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC   Candidatus Brocadiaceae; Brocadia.
OX   NCBI_TaxID=380242 {ECO:0000313|EMBL:KKO18081.1, ECO:0000313|Proteomes:UP000034954};
RN   [1] {ECO:0000313|EMBL:KKO18081.1, ECO:0000313|Proteomes:UP000034954}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RU1 {ECO:0000313|EMBL:KKO18081.1};
RX   PubMed=24267221; DOI=10.1186/1471-2180-13-265;
RA   Ferousi C., Speth D.R., Reimann J., Op den Camp H.J., Allen J.W.,
RA   Keltjens J.T., Jetten M.S.;
RT   "Identification of the type II cytochrome c maturation pathway in anammox
RT   bacteria by comparative genomics.";
RL   BMC Microbiol. 13:265-265(2013).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a quinol + nitrate = a quinone + H2O + nitrite;
CC         Xref=Rhea:RHEA:56144, ChEBI:CHEBI:15377, ChEBI:CHEBI:16301,
CC         ChEBI:CHEBI:17632, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; EC=1.7.5.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001854};
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KKO18081.1}.
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DR   EMBL; LAQJ01000295; KKO18081.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M2USW0; -.
DR   PATRIC; fig|380242.3.peg.3975; -.
DR   Proteomes; UP000034954; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd02776; MopB_CT_Nitrate-R-NarG-like; 1.
DR   CDD; cd02750; MopB_Nitrate-R-NarG-like; 1.
DR   Gene3D; 3.40.50.12440; -; 5.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR017840; DMSO_Rdtase_II_Mopterin_su.
DR   InterPro; IPR037943; MopB_CT_Nitrate-R-NarG-like.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR   InterPro; IPR027467; MopterinOxRdtase_cofactor_BS.
DR   NCBIfam; TIGR03479; DMSO_red_II_alp; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   PANTHER; PTHR43105:SF2; RESPIRATORY NITRATE REDUCTASE 2 ALPHA CHAIN; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR   PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR   PROSITE; PS00551; MOLYBDOPTERIN_PROK_1; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000034954}.
FT   DOMAIN          54..118
FT                   /note="4Fe-4S Mo/W bis-MGD-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51669"
SQ   SEQUENCE   910 AA;  103252 MW;  4EE8CB99A2973BD1 CRC64;
     MSQDESIRAS EVLAGQGEKV LLPALDLLEH ISEPIGKYPY QGWESLYREQ LDYDYFGRTT
     HSVNCTGSCT WKVYVKNNIA FKEEQYADYP DINASLPTYN PRGCQKGANY KEYVYGPQRL
     KYPLMRAGAR GEGKWRKASW EEATSYIANK MVNAISNYGP DTVTFYSANP AKFAITYTGG
     VRLANLIGAV VCSFYDWVSD LPPGEPITWG VQTDSCEAAD WFNSKYIIVW GSNILETRIP
     DAHFLTEARM HGTRIVAIFP EYNPTSIHAD MYVPVKPGTD CALALCMANV IMNEKLYDET
     YIKQYTDMPI LVRMDSGKFL RENDMVQDGS PDKFYVWDLS LDRPALVPGT KGTLNTIGWT
     LNLGSMNPAL EGTFTINTLS GEIKVTTVFS LLKQKLATYD PPHVSVITGV DADLVTQIAR
     EFAKTKPARI IGGAGTNHHY HNDLMSRSHI LLAAMTGNVG IQGGGFDYYV GQERFWPEDG
     FVKLAYPLGR SKQRFQPTTL WTYVHAHIAS EVNNLWPRPM IDYIRESVSN GWMPLYPEGT
     LDNGKSPKVL IIWGANYLNQ AKGFESILTN LWPKLDLIVD IDFRMNTTGL YADVILPAAS
     MFEKWDLSVT DLHSYINPFT PIIEPQMDSK TDWQIWQLLA KALQDTKFSF TDILPGGITL
     TRDFSTLVND FTENGSLASD KSAGQCILDN AVETKGMTMD GINQQPRRFV ATHEERTSDI
     KEGVAYYGFQ RMYELKRPLS TLTGRQQFYI DHQWFLDFGE QLPAYKPPVD EDKYPLRWNT
     PHGRWSIHSV WRDAKYQLRL QRGRPIVHLN PAEAQARSLA DNDAIEIYND HGKIVAQLCI
     SQRIPAGMAH MYHGWERYNF EKGGFQSPTT IRMKPTQLVG GYGQLEFRFN YWGPTASQRD
     TRVNIRKYIS
//