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Database: UniProt
Entry: A0A0M2ZGV0_9MYCO
LinkDB: A0A0M2ZGV0_9MYCO
Original site: A0A0M2ZGV0_9MYCO 
ID   A0A0M2ZGV0_9MYCO        Unreviewed;       500 AA.
AC   A0A0M2ZGV0;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   25-OCT-2017, entry version 18.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=BST23_21270 {ECO:0000313|EMBL:ORA61511.1};
OS   Mycobacterium elephantis.
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=81858 {ECO:0000313|EMBL:ORA61511.1, ECO:0000313|Proteomes:UP000192772};
RN   [1] {ECO:0000313|EMBL:ORA61511.1, ECO:0000313|Proteomes:UP000192772}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FI-09383 {ECO:0000313|EMBL:ORA61511.1,
RC   ECO:0000313|Proteomes:UP000192772};
RA   Tortoli E., Trovato A., Cirillo D.M.;
RT   "The new phylogeny of genus Mycobacterium.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:ORA61511.1}.
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DR   EMBL; MVHP01000031; ORA61511.1; -; Genomic_DNA.
DR   RefSeq; WP_046753612.1; NZ_MVHP01000031.1.
DR   EnsemblBacteria; KKW63098; KKW63098; AAV95_18970.
DR   Proteomes; UP000192772; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000192772};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895}.
FT   NP_BIND     201    208       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   500 AA;  56089 MW;  E0973FC4F107E5C2 CRC64;
     MTADPDPPFV SVWNTVVAEL NGETRPADAT NGDPATPTLT PQQRAWLKLV KPLVITEGFA
     LLSVPTPFVQ NEIERHLREP IITALSRQLG QRVELGVRIA APSPDDTEDS AGGFSSPPPL
     EPDEVDEVSE ALASAEESWP RYFANRGHLN PAADEDTAVN LNRRYTFETF VIGASNRFAH
     AATLAIAEAP ARAYNPLFIW GESGLGKTHL LHAAGNYAQR LFPGMRVKYV STEEFTNDFI
     NSLRDDRKAS FKRSYRDIDV LLVDDIQFIE GKEGIQEEFF HTFNTLHNAN KQIVISSDRP
     PKQLATLEDR LRTRFEWGLI TDVQPPELET RIAILRKKAQ MDRLDVPDDV LELIASSIER
     NIRELEGALI RVTAFASLNK TPIDRSLAEI VLRDLISDAS TMQISAAAIM AATAEYFETT
     VEELRGPGKT RALAQSRQIA MYLCRELTDL SLPKIGQAFG RDHTTVMYAE KKIRAEMAER
     REVFDHVKEL TTRIRQRAKR
//
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