ID   A0A0M3HXJ4_ASCLU        Unreviewed;       626 AA.
AC   A0A0M3HXJ4;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=PA domain-containing protein {ECO:0000313|WBParaSite:ALUE_0000805901-mRNA-1};
OS   Ascaris lumbricoides (Giant roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0000805901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ALUE_0000805901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0M3HXJ4; -.
DR   WBParaSite; ALUE_0000805901-mRNA-1; ALUE_0000805901-mRNA-1; ALUE_0000805901.
DR   Proteomes; UP000036681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd02121; PA_GCPII_like; 1.
DR   Gene3D; 3.50.30.30; -; 3.
DR   Gene3D; 3.40.630.10; Zn peptidases; 2.
DR   InterPro; IPR046450; PA_dom_sf.
DR   InterPro; IPR003137; PA_domain.
DR   InterPro; IPR007484; Peptidase_M28.
DR   InterPro; IPR039373; Peptidase_M28B.
DR   PANTHER; PTHR10404:SF46; GLUTAMATE CARBOXYPEPTIDASE 2 HOMOLOG; 1.
DR   PANTHER; PTHR10404; N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE; 1.
DR   Pfam; PF02225; PA; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF52025; PA domain; 2.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..33
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        45..67
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          342..428
FT                   /note="PA"
FT                   /evidence="ECO:0000259|Pfam:PF02225"
FT   DOMAIN          540..591
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
SQ   SEQUENCE   626 AA;  69590 MW;  516E2045832A6BE5 CRC64;
     MVTVLKTNAQ LLYIYVYNAT IVIALNLAVR LWLPKANALC SKAMMRATSV LGVGFVAIVL
     VGLLGVYHTA HPARQPRPET IEDYHQSISE KLIANVEGEN IKENLRLLTT LPHPAGTRAN
     TRVAEKIADL WRKNGLADVH YLKYEVLLSY PDYDRPNHVY IIDEDGRIEF ASKGVSPVII
     PEEQGAEDVH YLKYEVLLSY PDYDRPNHVY IIDEDGRIEF ASKGVSPVII PEEQGAEGDG
     SVGEGPDENI GKQLHAGFHA CKSNMHSDQQ HQRLQVPVLL LDGNCSIGAG VQWVAYSGNG
     TAQGEVVYCH HGRVEDFERL DRLALGCAGV HWVAYSGNGT AQGEVVYCHH GRVEDFERLD
     RLGITVKGKI ALLRYGNGFR GDKVRNAQMN GAIGAILYSD PAEVARMGPY PEKVYPNTEW
     MPLEGAQRGS IMRGNGDPLS PLYPSKKDLY RTKTVQEAKN DGTLPTIPVL PISYSDAFQI
     LSRMQGRMVP LDWQGGLNIS YRLGPRLGDG ATVRIDVRSS LQTRYHEAAR LAVILRTIRN
     VIGYIHGADD PDRYVILGNH FDAWVYGSID PNSGTAVLAE VARAITQTIN ETNWRPGILF
     FWCVNPITTV IEWLMHMHVS FETFNV
//