ID   A0A0M3I9H8_ASCLU        Unreviewed;       353 AA.
AC   A0A0M3I9H8;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   28-JUN-2023, entry version 23.
DE   SubName: Full=Neur_chan_memb domain-containing protein {ECO:0000313|WBParaSite:ALUE_0001411601-mRNA-1};
OS   Ascaris lumbricoides (Giant roundworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Ascarididae; Ascaris.
OX   NCBI_TaxID=6252 {ECO:0000313|Proteomes:UP000036681, ECO:0000313|WBParaSite:ALUE_0001411601-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ALUE_0001411601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
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DR   AlphaFoldDB; A0A0M3I9H8; -.
DR   WBParaSite; ALUE_0001411601-mRNA-1; ALUE_0001411601-mRNA-1; ALUE_0001411601.
DR   Proteomes; UP000036681; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   CDD; cd19051; LGIC_TM_cation; 1.
DR   Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR038050; Neuro_actylchol_rec.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   PANTHER; PTHR18945:SF410; ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-TYPE DES-2; 1.
DR   PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR   Pfam; PF02932; Neur_chan_memb; 1.
DR   SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        28..51
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        63..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        322..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          35..336
FT                   /note="Neurotransmitter-gated ion-channel transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF02932"
SQ   SEQUENCE   353 AA;  40429 MW;  6AF78243B8E495AC CRC64;
     RRQEVKFECC HNNYTLLIYT LYLQRKPLFY LINLVTPTSV ITLIAIVGFF SAPTVNGIRE
     EKISLGITTL LSMSILILMV SDKMPSTSSF IPLIGWFYFS MIMLISSGTL AASLIIYTQK
     KGAIGKRPPQ NWMRFYKWLG KLIRFQMPIA MKRIYKVTSK RKHSSGGMFI RNKGRQHHSR
     IRKKQLAEPV LLTITKSPDR PPIPTTIGDN EEEMKLIDVD EDEPPQTADS NMPVANVRHK
     SISQKSDSLS KETKAFYEEI STGIKRRNTT RHNVGMVRTG TTIRKNLHNC SRNLFAANVK
     NNGKLAEIEY DWIAAVIERC CFIVFFVLFL FTSFGINAIG LIYWYNVGDR IVQ
//