ID   A0A0M3JQS4_ANISI        Unreviewed;       562 AA.
AC   A0A0M3JQS4;
DT   11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT   11-NOV-2015, sequence version 1.
DT   22-FEB-2023, entry version 18.
DE   RecName: Full=Trehalase {ECO:0000256|ARBA:ARBA00019905, ECO:0000256|RuleBase:RU361180};
DE            EC=3.2.1.28 {ECO:0000256|ARBA:ARBA00012757, ECO:0000256|RuleBase:RU361180};
DE   AltName: Full=Alpha-trehalose glucohydrolase {ECO:0000256|RuleBase:RU361180};
OS   Anisakis simplex (Herring worm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC   Anisakis simplex complex.
OX   NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001003001-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:ASIM_0001003001-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (FEB-2017) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-
CC         glucose; Xref=Rhea:RHEA:32675, ChEBI:CHEBI:15377, ChEBI:CHEBI:15903,
CC         ChEBI:CHEBI:16551, ChEBI:CHEBI:17925; EC=3.2.1.28;
CC         Evidence={ECO:0000256|ARBA:ARBA00001576,
CC         ECO:0000256|RuleBase:RU361180};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 37 family.
CC       {ECO:0000256|ARBA:ARBA00005615, ECO:0000256|RuleBase:RU361180}.
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DR   AlphaFoldDB; A0A0M3JQS4; -.
DR   WBParaSite; ASIM_0001003001-mRNA-1; ASIM_0001003001-mRNA-1; ASIM_0001003001.
DR   Proteomes; UP000036680; Unplaced.
DR   GO; GO:0004555; F:alpha,alpha-trehalase activity; IEA:UniProtKB-EC.
DR   GO; GO:0005991; P:trehalose metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR001661; Glyco_hydro_37.
DR   InterPro; IPR018232; Glyco_hydro_37_CS.
DR   PANTHER; PTHR23403; TREHALASE; 1.
DR   PANTHER; PTHR23403:SF5; TREHALASE; 1.
DR   Pfam; PF01204; Trehalase; 1.
DR   PRINTS; PR00744; GLHYDRLASE37.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR   PROSITE; PS00927; TREHALASE_1; 1.
DR   PROSITE; PS00928; TREHALASE_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361180};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361180}.
SQ   SEQUENCE   562 AA;  65201 MW;  5DA6FF699E968D11 CRC64;
     LLRAVNIHSI FNDSKTFVDM PMKQDPKHVL DEFNKRFPQM TAERIERDDL IAFLNEFFSP
     PGTELEDCEL SDWQPYPPDL MAISDKTLRK FALDLNQIWK MLCRKVKPDL KNSDRHSLIY
     VPNEFVVPGG RFREYYYWDA YWIIKGLLAC GMNVTTKSML ENLASVVDRY GFVPNGGRVY
     YLERSQPPFL SSMVYEYFEK THDIDFLRDI LPALAKEFHF WQTNRTVSVI GLNQSNYTVY
     RYRTNSNVPR PESYREDITV AKQLPAEARA LLYQNIASSA ESGWDFSTRW FADGETLASV
     QTTSIVPVDL NAIMCLNMDL LKYFYRTVGN FSESKKYNRM KNDFMYAMQY VFYNDTHGAW
     FDYNIETLKH NTKFYASIAL PLFGDCYQLL NMAKSERIYK FMSKSGVFDY PSGVPTSLID
     SGQQWDFPNG WSPLNHMIIE GLRKSLNPEM QEQAFKLAQK WVHGNYKVFE ATGHMWEKYD
     VIGTVPKPGV GGEYSVQPGF GWSNGAILDL LVTYRHRMKL LDDSQESTTT TKSTAIPHPS
     LLIYLTTTMA VFFVQQRYAL IC
//