ID A0A0M3JRV7_ANISI Unreviewed; 333 AA.
AC A0A0M3JRV7;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 3.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Homeobox protein Hmx (inferred by orthology to a D. melanogaster protein) {ECO:0000313|WBParaSite:ASIM_0001066301-mRNA-1};
GN ORFNames=ASIM_LOCUS10221 {ECO:0000313|EMBL:VDK42555.1};
OS Anisakis simplex (Herring worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC Anisakis simplex complex.
OX NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001066301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ASIM_0001066301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (MAR-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK42555.1, ECO:0000313|Proteomes:UP000267096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the HMX homeobox family.
CC {ECO:0000256|ARBA:ARBA00038165}.
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DR EMBL; UYRR01030989; VDK42555.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M3JRV7; -.
DR WBParaSite; ASIM_0001066301-mRNA-1; ASIM_0001066301-mRNA-1; ASIM_0001066301.
DR Proteomes; UP000036680; Unplaced.
DR Proteomes; UP000267096; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR CDD; cd00086; homeodomain; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR017970; Homeobox_CS.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR020479; Homeobox_metazoa.
DR PANTHER; PTHR46110; HOMEOBOX PROTEIN HMX; 1.
DR PANTHER; PTHR46110:SF3; HOMEOBOX PROTEIN HMX; 1.
DR Pfam; PF00046; Homeodomain; 1.
DR PRINTS; PR00024; HOMEOBOX.
DR SMART; SM00389; HOX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00027; HOMEOBOX_1; 1.
DR PROSITE; PS50071; HOMEOBOX_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000267096};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 148..208
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 150..209
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 66..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 66..83
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..114
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..133
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 333 AA; 36219 MW; 08579683AE1A988C CRC64;
MALALVEKTQ VAAERLSTSS SPNLSSPPTD LFRLVSSAYH HHRSPHQQSY RKFDTNNTTN
IEQRNETLQN SSASEQRTPC AVEHSSVNAE GRLNEGVVQT ANGCYSSVNG SSPLESDCEE
DDEEDDEEGD TTRASDDDAT IAATDSAHRK KKTRTVFSRQ QVSQLEMTFD MKRYLSSQER
AHLASTLRLT ETQVKIWFQN RRNKWKRQAV TEMDSSAGLN IHRSNIFAPH LQQIGSQCDR
LPTSHQMTTS LPLSATTAIP ALNGSLIHPA AVLFRSSASS ATSSASSPPQ QTTTPFSFVA
NPESNSASAS AAAAAKLFYG TYGAIAAAHA QLI
//
