ID A0A0M3JYU3_ANISI Unreviewed; 523 AA.
AC A0A0M3JYU3;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=GATase cobBQ-type domain-containing protein {ECO:0000313|WBParaSite:ASIM_0001363401-mRNA-1};
GN ORFNames=ASIM_LOCUS13062 {ECO:0000313|EMBL:VDK48830.1};
OS Anisakis simplex (Herring worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC Anisakis simplex complex.
OX NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001363401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ASIM_0001363401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK48830.1, ECO:0000313|Proteomes:UP000267096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004953}.
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DR EMBL; UYRR01031305; VDK48830.1; -; Genomic_DNA.
DR WBParaSite; ASIM_0001363401-mRNA-1; ASIM_0001363401-mRNA-1; ASIM_0001363401.
DR UniPathway; UPA00148; -.
DR Proteomes; UP000036680; Unplaced.
DR Proteomes; UP000267096; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR CDD; cd05389; CobQ_N; 1.
DR CDD; cd01750; GATase1_CobQ; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00028; CobQ; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR002586; CobQ/CobB/MinD/ParA_Nub-bd_dom.
DR InterPro; IPR033949; CobQ_GATase1.
DR InterPro; IPR047045; CobQ_N.
DR InterPro; IPR004459; CobQ_synth.
DR InterPro; IPR011698; GATase_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00313; cobQ; 1.
DR PANTHER; PTHR21343:SF1; COBYRIC ACID SYNTHASE; 1.
DR PANTHER; PTHR21343; DETHIOBIOTIN SYNTHETASE; 1.
DR Pfam; PF01656; CbiA; 1.
DR Pfam; PF07685; GATase_3; 1.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51274; GATASE_COBBQ; 1.
PE 3: Inferred from homology;
KW Cobalamin biosynthesis {ECO:0000256|ARBA:ARBA00022573};
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000267096};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 119..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 181..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 7..250
FT /note="CobQ/CobB/MinD/ParA nucleotide binding"
FT /evidence="ECO:0000259|Pfam:PF01656"
FT DOMAIN 276..461
FT /note="CobB/CobQ-like glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF07685"
SQ SEQUENCE 523 AA; 58021 MW; F632CC12992EA746 CRC64;
MTRLHPVMLA GTASDVGKSV LATALCRIFK QDGYHPAPFK AQNMALNSFV TPDGLEIGRS
QAVQAEAACV QCETDMNPIL LKPTTDCTSQ VVLNGRPIGN STASTYFCKD RIDELRTQVI
TFNAMLYLIF LIFFQVCAAF DRLTHKYNPI VMEGAGSVSE LNLQDRDLVN MPMARHAQAD
VFLVADINLG GVFASLYGSI ALQQPIDRRL IKGIIVNKFR GDIRLFDSGV KMLEEICGVP
VLGVIPFYRD IYIEEEDCVQ LQTRHRNALS SQNKINVAVI LMRHLSNFTD FDSLERDPRV
HLFYTNNVSE IQKAHIILLP GTKNTIDDLR EIRANGVAKA IVSAYRDGNA TVLGICGGYQ
LMGKEVRDPN AVESDIRCLP GLSLLPVTTT MNNIKTTCQT KFKVFGSDQL CSGYEIHNGI
TEMLGEVTPL NILDDGTEEG CYVAEGRCMG TYIHGILDNA PFIDLLLKGH LGELSKKTEF
DYAQFKEEQY DKLAAHLREH LNVDLMYQIL KGSCCDGIVQ TTD
//
