ID A0A0M3KBM2_ANISI Unreviewed; 561 AA.
AC A0A0M3KBM2;
DT 11-NOV-2015, integrated into UniProtKB/TrEMBL.
DT 11-NOV-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Putative kunitz-type protease inhibitor (inferred by orthology to a S. mansoni protein) {ECO:0000313|WBParaSite:ASIM_0001836901-mRNA-1};
GN ORFNames=ASIM_LOCUS17770 {ECO:0000313|EMBL:VDK61413.1};
OS Anisakis simplex (Herring worm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Ascaridomorpha; Ascaridoidea; Anisakidae; Anisakis;
OC Anisakis simplex complex.
OX NCBI_TaxID=6269 {ECO:0000313|Proteomes:UP000036680, ECO:0000313|WBParaSite:ASIM_0001836901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:ASIM_0001836901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (FEB-2017) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDK61413.1, ECO:0000313|Proteomes:UP000267096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UYRR01034555; VDK61413.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M3KBM2; -.
DR WBParaSite; ASIM_0001836901-mRNA-1; ASIM_0001836901-mRNA-1; ASIM_0001836901.
DR Proteomes; UP000036680; Unplaced.
DR Proteomes; UP000267096; Unassembled WGS sequence.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR CDD; cd00109; Kunitz-type; 3.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 4.
DR InterPro; IPR006150; Cys_repeat_1.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR InterPro; IPR028150; Lustrin_cystein.
DR InterPro; IPR020901; Prtase_inh_Kunz-CS.
DR PANTHER; PTHR10083; KUNITZ-TYPE PROTEASE INHIBITOR-RELATED; 1.
DR PANTHER; PTHR10083:SF217; PROTEIN CBG23496; 1.
DR Pfam; PF00014; Kunitz_BPTI; 4.
DR Pfam; PF14625; Lustrin_cystein; 1.
DR PRINTS; PR00759; BASICPTASE.
DR SMART; SM00131; KU; 4.
DR SMART; SM00289; WR1; 1.
DR SUPFAM; SSF57362; BPTI-like; 4.
DR PROSITE; PS00280; BPTI_KUNITZ_1; 2.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 4.
PE 4: Predicted;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Reference proteome {ECO:0000313|Proteomes:UP000267096};
KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}.
FT DOMAIN 106..168
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 233..283
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 424..454
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 471..521
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 70..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 294..397
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..321
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..395
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 561 AA; 60940 MW; 3AC7F235DA8C9EF4 CRC64;
KSFSGEVDPC KRQPFRGRCP AVSGGQQTRS QMFSNLGHCS KDTNEPRLYR YKEECEDACL
NVVRSNNNVQ KTEDIASPTA SSTSTQPTTS TSVTSDESRK SAPNDCTSAV DAGPCESSVS
RWYYDANEQT CKPFSYSGQW DCCIISTIPG CGGNGNNYLT KFACERRCTP VLDSSIKCPN
GAEPLKNVHG VPTTCAKKSC PSDHKCTKVE QNSICCPVPE DESKKSSSKA DVCALPKERG
PCDRYELRFY YNSDMKECKY FFFGGCEGNA NNFERVEDCE SACGRGRKAL RIESPQTVQT
KPTTAAPTTT AMSQEATTVE QIPEAEETEA SKVPGIVEHP TSASTKSAPS TAAKNVDSVH
LTGEPETSVN IDTTSTTVTT TPEQPTTQSS APSRKIVTDP PVEPLVSLIK PQDINQPDII
PPLPETKTCD VFTYSGCSGN GNNFANREEC LSICNRQVNT KTSQPSAASL CAHKINPGDC
KGEFERFAFD TETGKCRPFI YGGCGGNGNN FASLEECAQR CHPQGCCFSS NLLTFILSRT
YNICLFDMSS IVSYHFCAIL H
//
