ID   A0A0M4CYS7_SPHS1        Unreviewed;       798 AA.
AC   A0A0M4CYS7;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Glucose dehydrogenase {ECO:0000313|EMBL:ALC12422.1};
GN   ORFNames=LH20_10710 {ECO:0000313|EMBL:ALC12422.1};
OS   Sphingopyxis sp. (strain 113P3).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingopyxis.
OX   NCBI_TaxID=292913 {ECO:0000313|EMBL:ALC12422.1, ECO:0000313|Proteomes:UP000061305};
RN   [1] {ECO:0000313|EMBL:ALC12422.1, ECO:0000313|Proteomes:UP000061305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=113P3 {ECO:0000313|EMBL:ALC12422.1,
RC   ECO:0000313|Proteomes:UP000061305};
RX   PubMed=26472829;
RA   Ohtsubo Y., Nagata Y., Numata M., Tsuchikane K., Hosoyama A., Yamazoe A.,
RA   Tsuda M., Fujita N., Kawai F.;
RT   "Complete Genome Sequence of Polyvinyl Alcohol-Degrading Strain
RT   Sphingopyxis sp. 113P3 (NBRC 111507).";
RL   Genome Announc. 3:e01169-15(2015).
CC   -!- COFACTOR:
CC       Name=pyrroloquinoline quinone; Xref=ChEBI:CHEBI:58442;
CC         Evidence={ECO:0000256|ARBA:ARBA00001931};
CC   -!- SIMILARITY: Belongs to the bacterial PQQ dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00008156}.
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DR   EMBL; CP009452; ALC12422.1; -; Genomic_DNA.
DR   RefSeq; WP_053554146.1; NZ_CP009452.1.
DR   AlphaFoldDB; A0A0M4CYS7; -.
DR   STRING; 292913.LH20_10710; -.
DR   KEGG; sphp:LH20_10710; -.
DR   PATRIC; fig|292913.6.peg.2164; -.
DR   OrthoDB; 9794322at2; -.
DR   Proteomes; UP000061305; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR   GO; GO:0048038; F:quinone binding; IEA:InterPro.
DR   CDD; cd10280; PQQ_mGDH; 1.
DR   Gene3D; 2.140.10.10; Quinoprotein alcohol dehydrogenase-like superfamily; 2.
DR   InterPro; IPR018391; PQQ_beta_propeller_repeat.
DR   InterPro; IPR017511; PQQ_mDH.
DR   InterPro; IPR002372; PQQ_repeat.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   NCBIfam; TIGR03074; PQQ_membr_DH; 1.
DR   PANTHER; PTHR32303; QUINOPROTEIN ALCOHOL DEHYDROGENASE (CYTOCHROME C); 1.
DR   PANTHER; PTHR32303:SF4; QUINOPROTEIN GLUCOSE DEHYDROGENASE; 1.
DR   Pfam; PF01011; PQQ; 1.
DR   Pfam; PF13360; PQQ_2; 2.
DR   SMART; SM00564; PQQ; 6.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000061305};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..36
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        42..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        66..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        88..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        122..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          627..649
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   798 AA;  85684 MW;  DC0035FDF82B6E8F CRC64;
     MNRLRQIFPA PWLALLTGLI LALIAVVLLV GGAWLAALGG SPYYLVTGAA MLAAGALLMR
     GSMAGGWLYA AILFFTLIWA FWEVGANGWA LVPRIIAPVF LLILVFFAVA SLSRRPHRWR
     RALAASALAI GLVAAGGAML GWLNTARPLR DLPGERWAMA DPALMEAGSN WPAYGGTYSA
     RRYSPLDQIT PANVGKLKRA WLIHTGDLPS KAAHGTYGAE NTPLKIGDSL YVCTPKNIVL
     ALDPATGRQK WRFDPKVPDD AIPYTAACRG VSYYGVPNPG AGQPCAQRII LGTLDARLFA
     LDAATGRPCQ DFGSNGEVDT KIGMGPTPPG YVSINSPPTI VRGIIVTGHQ VLDGQDRWAP
     SGVIRGFDAV TGKLAWAWDM MNPDWKGYPP PGETWARGTP NMWTIASGDE ALGLVYLPMG
     NAAADYYSSL RRGPENEYAT SLVALDVTTG KPRWRFQAVK KDVWDYDFGA QATLIDFPGP
     EGATPALVLP SKQGDIYILD RRTGRPLTPI GTIKAPRGGV EPAERAPTQI VSLWHSLRGT
     DLTERDMWGM SPIDQMVCRI QFRKASYQGF YTPPTSDRRS IEYPGYNGGT DWGGVAVDPV
     RGVIIANYND MPNYVRLVPR AEADKRGWAP RDQARGNIGG AEGAGDPQAG TPYAIDVNAG
     WRLPWTGLLC KQPPYGGIRA IDIATGKTIW DRPLGTARTN GPFGIPSMLP VTIGTPNNGG
     AAVTAGGLIF IAAATDNLIR AIDLKTGRTL WTDVLPAGGQ ATPMTYEANG KQYVVIYAGG
     HHFMETPIGD EVIAYALP
//