ID A0A0M4H777_9ACTO Unreviewed; 328 AA.
AC A0A0M4H777;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Phosphoglycerate dehydrogenase {ECO:0000313|EMBL:ALC99920.1};
GN ORFNames=AM609_11430 {ECO:0000313|EMBL:ALC99920.1};
OS Actinomyces sp. oral taxon 414.
OC Bacteria; Actinomycetota; Actinomycetes; Actinomycetales; Actinomycetaceae;
OC Actinomyces.
OX NCBI_TaxID=712122 {ECO:0000313|EMBL:ALC99920.1, ECO:0000313|Proteomes:UP000061022};
RN [1] {ECO:0000313|Proteomes:UP000061022}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F0588 {ECO:0000313|Proteomes:UP000061022};
RA Holder M.E., Ajami N.J., Petrosino J.F.;
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP012590; ALC99920.1; -; Genomic_DNA.
DR RefSeq; WP_053587364.1; NZ_CP012590.1.
DR AlphaFoldDB; A0A0M4H777; -.
DR STRING; 712122.AM609_11430; -.
DR KEGG; acq:AM609_11430; -.
DR PATRIC; fig|712122.3.peg.2576; -.
DR OrthoDB; 4324715at2; -.
DR Proteomes; UP000061022; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR43333; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR43333:SF1; 2-HACID_DH_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02826; 2-Hacid_dh_C; 1.
DR SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 152..175
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 107..289
FT /note="D-isomer specific 2-hydroxyacid dehydrogenase NAD-
FT binding"
FT /evidence="ECO:0000259|Pfam:PF02826"
SQ SEQUENCE 328 AA; 34098 MW; E4A37E2630DBBD69 CRC64;
MKILLTDTGY IDPSLIRDAG HDVVLFDETA PVPAEHRDAE GLVLWGGGGS GSAEILADMP
GYLTRLRWIQ TLAAGPDNVL AAGFPTSVAI TSGRHFHDRT VAEHAAALAL GCVRNLPTAV
RAADRHEWEP TLGGAHPIHD PDRLTTLLRA RVLVWGFGAI GIATAQLLTA FGANVRGVAR
SAGRRAGFEV IAVDDVESAL PWTDLLVMVL PSTPQTAGAL NAERLALLPR RAVVVNVGRG
ATVDQAALEA ALRSGAISAA GLDVTDPEPL PADSTLWDAP NLLLTPHAAG GRVVGAVERI
IANAAAVEAT PLGEPITGLE AQVPRSSH
//
