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Database: UniProt
Entry: A0A0M4QPE3_9MICC
LinkDB: A0A0M4QPE3_9MICC
Original site: A0A0M4QPE3_9MICC 
ID   A0A0M4QPE3_9MICC        Unreviewed;       489 AA.
AC   A0A0M4QPE3;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   25-OCT-2017, entry version 19.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AOC05_15395 {ECO:0000313|EMBL:ALE93384.1};
OS   Arthrobacter alpinus.
OC   Bacteria; Actinobacteria; Micrococcales; Micrococcaceae; Arthrobacter.
OX   NCBI_TaxID=656366 {ECO:0000313|EMBL:ALE93384.1, ECO:0000313|Proteomes:UP000062833};
RN   [1] {ECO:0000313|Proteomes:UP000062833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R3.8 {ECO:0000313|Proteomes:UP000062833};
RA   See-Too W.S., Chan K.G.;
RT   "Complete genome of Arthrobacter alpinus strain R3.8.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00735475}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP012677; ALE93384.1; -; Genomic_DNA.
DR   RefSeq; WP_062008106.1; NZ_CP012677.1.
DR   EnsemblBacteria; ALE93384; ALE93384; AOC05_15395.
DR   KEGG; aaq:AOC05_15395; -.
DR   PATRIC; fig|656366.3.peg.3332; -.
DR   KO; K02313; -.
DR   Proteomes; UP000062833; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000062833};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000062833}.
FT   DOMAIN      180    310       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      392    461       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     188    195       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
FT   COILED      461    488       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   489 AA;  55080 MW;  1CDB4B3009E941F1 CRC64;
     MGTEGINTEE INDVGSSWRR VIRILEQDER VSPRQRGFVV LTQPQGLIGN TLLVAVPNEL
     TREVLQTQLN TALVEALRQV FPAEISCAFS VNADLVPTRK EEVAAPEQVP VRADRNDRVE
     RIERSERIDI ASKPSPMLPS TSQEFGRLNP KYVFDSFVIG SSNRFAHAAA VAVAEAPAKA
     YNPLFIYGDS GLGKTHLLHA IGHYARRLYN GIRVRYVNSE EFTNDFINSI RDDEGASFKQ
     LYRNVDILLI DDIQFLANKD ATQEEFFHTF NALHNHNKQV VITSDLPPKR LQGFEERMRS
     RFEWGLLTDV QPPELETRIA ILRKKAIGEG LSAPDDALEY IASKISTNIR ELEGALIRVT
     AFASLNRQPV DVGLAEMVLK DLITDDGAQE ITSTAILGQT AAYFNISLEE LCSKSRTRTL
     VTARQIAMYL CRELTDMSLP KIGQEFGGRD HTTVMHADRK IRELMAERRA IYNQVTELTN
     KIKQQQREG
//
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