ID A0A0M7B8F4_9RHOB Unreviewed; 316 AA.
AC A0A0M7B8F4;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE SubName: Full=L-carnitine dehydrogenase {ECO:0000313|EMBL:CUH34704.1};
DE EC=1.1.1.108 {ECO:0000313|EMBL:CUH34704.1};
GN Name=lcdH {ECO:0000313|EMBL:CUH34704.1};
GN ORFNames=JSE7799_01063 {ECO:0000313|EMBL:CUH34704.1};
OS Jannaschia seosinensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia.
OX NCBI_TaxID=313367 {ECO:0000313|EMBL:CUH34704.1, ECO:0000313|Proteomes:UP000049455};
RN [1] {ECO:0000313|EMBL:CUH34704.1, ECO:0000313|Proteomes:UP000049455}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CECT 7799 {ECO:0000313|EMBL:CUH34704.1,
RC ECO:0000313|Proteomes:UP000049455};
RA Jackson K.R., Lunt B.L., Fisher J.N.B., Gardner A.V., Bailey M.E.,
RA Deus L.M., Earl A.S., Gibby P.D., Hartmann K.A., Liu J.E., Manci A.M.,
RA Nielsen D.A., Solomon M.B., Breakwell D.P., Burnett S.H., Grose J.H.;
RL Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009463}.
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DR EMBL; CYPR01000058; CUH34704.1; -; Genomic_DNA.
DR RefSeq; WP_055662705.1; NZ_CYPR01000058.1.
DR AlphaFoldDB; A0A0M7B8F4; -.
DR STRING; 313367.JSE7799_01063; -.
DR OrthoDB; 9803287at2; -.
DR Proteomes; UP000049455; Unassembled WGS sequence.
DR GO; GO:0047728; F:carnitine 3-dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR48075:SF1; LAMBDA-CRYSTALLIN HOMOLOG; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00067; 3HCDH; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000313|EMBL:CUH34704.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000049455}.
FT DOMAIN 6..184
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 189..251
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 316 AA; 34070 MW; 6FBBE8216C246422 CRC64;
MSGDTKIAIV GSGLIGCAWA VSFARGGCTV VLFDQNDETT MHAPGRVRAI ANQMETAGLL
GGTTANGVAA RVRVAGNLGD ALDGAVHVQE NVPEKLDVKR TVFSELDVLA PHDAVLASST
SALLPSAFTE HLKGRARCVV AHPINPPSLI PAVEVVPAPW SDPEIVERTA QLMERIGQTP
IRMKREIDGF IMNRLQGALL QEAFRLVEQG IADPEDVDIG IREGLAPRWA LVGPFETIDL
NAPGGVRDYV DRYGGMYDTI AAGQRDNVDW RGPVLDRIDA ARRAVVPLEE IPDAQARRDR
RLIALMTHLR GASRDD
//
