ID A0A0M8MNZ5_9MICO Unreviewed; 334 AA.
AC A0A0M8MNZ5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=2-oxoisovalerate dehydrogenase {ECO:0000313|EMBL:KOS11364.1};
GN ORFNames=XI38_05775 {ECO:0000313|EMBL:KOS11364.1};
OS Microbacterium chocolatum.
OC Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Microbacteriaceae;
OC Microbacterium.
OX NCBI_TaxID=84292 {ECO:0000313|EMBL:KOS11364.1, ECO:0000313|Proteomes:UP000037737};
RN [1] {ECO:0000313|EMBL:KOS11364.1, ECO:0000313|Proteomes:UP000037737}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SIT 101 {ECO:0000313|EMBL:KOS11364.1,
RC ECO:0000313|Proteomes:UP000037737};
RA Li X., Xu Y.;
RT "Complete genome sequence of Microbacterium chocolatum SIT 101, a bacterium
RT enantioselectively hydrolyzing mesomeric diesters.";
RL Submitted (APR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS11364.1}.
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DR EMBL; LAVO01000005; KOS11364.1; -; Genomic_DNA.
DR RefSeq; WP_053547365.1; NZ_KQ440286.1.
DR AlphaFoldDB; A0A0M8MNZ5; -.
DR KEGG; mcw:A8L33_09665; -.
DR PATRIC; fig|84292.3.peg.1185; -.
DR OrthoDB; 3457658at2; -.
DR Proteomes; UP000037737; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000037737}.
FT DOMAIN 4..179
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 334 AA; 36157 MW; B8B800D560905D56 CRC64;
MTELTMAKAI TAGLRRAMAD DPKVLVMGED VGSLGGVFRV TDGLQAEFGA QRVIDTPLAE
SGIMGTAVGL AFRGFRPVVE IQFDGFVYPA FDQIVCQVAK LHYRTRGAVR MPITIRIPWA
GGVGAAEHHS ESPEAYFVHT SGLRVVAVSD PQDAYVSLRQ AIASDDPVVY FEPKRLYHLK
GKVDLSTDLA DAAPLGLARV VREGRDVTLL AYGAMVRTAV DAAEAEGISI EVIDLRSLSP
VDYRTLEASV RKTGRVVIAH EAAREAGVGA EVIASLTERC FHYLEAPPVR VTGHDIPYPP
AKLEKHHIPD LDRILDAVDR VLDRPNSRSE VVGS
//
