ID   A0A0M8N0H9_9HYPO        Unreviewed;       521 AA.
AC   A0A0M8N0H9;
DT   09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT   09-DEC-2015, sequence version 1.
DT   24-JAN-2024, entry version 31.
DE   RecName: Full=Vacuolar protein sorting-associated protein 17 {ECO:0000256|PIRNR:PIRNR011791};
GN   ORFNames=ESCO_003153 {ECO:0000313|EMBL:KOS18054.1};
OS   Escovopsis weberi.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Hypocreaceae; Escovopsis.
OX   NCBI_TaxID=150374 {ECO:0000313|EMBL:KOS18054.1, ECO:0000313|Proteomes:UP000053831};
RN   [1] {ECO:0000313|EMBL:KOS18054.1, ECO:0000313|Proteomes:UP000053831}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   de Man T.J., Stajich J.E., Kubicek C.P., Chenthamara K., Atanasova L.,
RA   Druzhinina I.S., Birnbaum S., Barribeau S.M., Teiling C., Suen G.,
RA   Currie C., Gerardo N.M.;
RT   "The genome of the fungus Escovopsis weberi, a specialized disease agent of
RT   ant agriculture.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the membrane-associated retromer complex which
CC       is essential in endosome-to-Golgi retrograde transport.
CC       {ECO:0000256|PIRNR:PIRNR011791}.
CC   -!- SUBUNIT: Component of the retromer complex.
CC       {ECO:0000256|PIRNR:PIRNR011791}.
CC   -!- SIMILARITY: Belongs to the VPS17 family.
CC       {ECO:0000256|PIRNR:PIRNR011791}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KOS18054.1}.
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DR   EMBL; LGSR01000022; KOS18054.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0M8N0H9; -.
DR   STRING; 150374.A0A0M8N0H9; -.
DR   OrthoDB; 1708746at2759; -.
DR   Proteomes; UP000053831; Unassembled WGS sequence.
DR   GO; GO:0005829; C:cytosol; IEA:GOC.
DR   GO; GO:0030904; C:retromer complex; IEA:InterPro.
DR   GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0042147; P:retrograde transport, endosome to Golgi; IEA:InterPro.
DR   CDD; cd06891; PX_Vps17p; 1.
DR   Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR   Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR   InterPro; IPR027267; AH/BAR_dom_sf.
DR   InterPro; IPR001683; PX_dom.
DR   InterPro; IPR036871; PX_dom_sf.
DR   InterPro; IPR014461; Retromer_complex_Vps17.
DR   InterPro; IPR037907; Vps17_PX.
DR   InterPro; IPR015404; Vps5_C.
DR   PANTHER; PTHR47433; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17; 1.
DR   PANTHER; PTHR47433:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 17; 1.
DR   Pfam; PF00787; PX; 1.
DR   Pfam; PF09325; Vps5; 1.
DR   PIRSF; PIRSF011791; Vps17; 1.
DR   SUPFAM; SSF64268; PX domain; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|PIRNR:PIRNR011791};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053831};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR011791}.
FT   DOMAIN          82..162
FT                   /note="PX"
FT                   /evidence="ECO:0000259|Pfam:PF00787"
FT   DOMAIN          218..401
FT                   /note="Sorting nexin/Vps5-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09325"
FT   REGION          1..52
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          412..521
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   521 AA;  57136 MW;  FF95E586C639A8AD CRC64;
     MAPPVPSAEP HEEAAFEQPA PERPLPSQEE AAPDAPAEEP AQLRKSTQPQ FRLQAKITGL
     ERTGKKDPIL RFDVHTNLPR FRTTQYRDVR RLHSEFIKLA EHLISANPEA LVPAVPPPLT
     SAGAGTDEDE SRVKALMQRW FNYVCGSEAL MMDDEMVLFV ESDFGYSPLV KRKQPATGVR
     RKILKQFAPP PDDTPELADA RPTVKLFYLG TMDAGHKVDK LVKARRGLGL AESDYGVKLG
     RMHVQEPHPG LANAYKKLGR VVQAVGDYHA AQATAEATTI GDPFQHHSQD AFIVKETLTN
     RQILIREFLQ AQEVTRGKLN SADRLKASSS VRREKVDEAI AALDEARENE LQLYNKTSRV
     TRNLVQERRK WFDRTATDLR MEIREFVLRE IEAERRTLAL LESVRGDIRS IDGTGGLSRL
     GREAHPVGRR TSLAASQGPK GDAWSGAPRR SDATSRTASG SFVAKVPEEG DGDEGQDAAG
     SVHGGAGAAG AGAAGLVGLE EDDEDRVDAR NAASRLATST F
//