ID A0A0M8P3Q5_9EURO Unreviewed; 382 AA.
AC A0A0M8P3Q5;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Cyclin-like domain-containing protein {ECO:0000259|SMART:SM00385};
GN ORFNames=ACN38_g9398 {ECO:0000313|EMBL:KOS39770.1};
OS Penicillium nordicum.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=229535 {ECO:0000313|EMBL:KOS39770.1, ECO:0000313|Proteomes:UP000037696};
RN [1] {ECO:0000313|EMBL:KOS39770.1, ECO:0000313|Proteomes:UP000037696}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DAOMC 185683 {ECO:0000313|EMBL:KOS39770.1,
RC ECO:0000313|Proteomes:UP000037696};
RA Nguyen H.D., Seifert K.A.;
RT "Genome sequencing of Penicillium nordicum.";
RL Submitted (AUG-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the SRB8-11 complex. The SRB8-11 complex is a
CC regulatory module of the Mediator complex which is itself involved in
CC regulation of basal and activated RNA polymerase II-dependent
CC transcription. The SRB8-11 complex may be involved in the
CC transcriptional repression of a subset of genes regulated by Mediator.
CC It may inhibit the association of the Mediator complex with RNA
CC polymerase II to form the holoenzyme complex. The SRB8-11 complex
CC phosphorylates the C-terminal domain (CTD) of the largest subunit of
CC RNA polymerase II. {ECO:0000256|ARBA:ARBA00025278}.
CC -!- SUBUNIT: Component of the SRB8-11 complex, a regulatory module of the
CC Mediator complex. {ECO:0000256|ARBA:ARBA00011612}.
CC -!- SIMILARITY: Belongs to the cyclin family.
CC {ECO:0000256|RuleBase:RU000383}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOS39770.1}.
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DR EMBL; LHQQ01000189; KOS39770.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0M8P3Q5; -.
DR STRING; 229535.A0A0M8P3Q5; -.
DR OrthoDB; 1332948at2759; -.
DR Proteomes; UP000037696; Unassembled WGS sequence.
DR GO; GO:0016538; F:cyclin-dependent protein serine/threonine kinase regulator activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd20546; CYCLIN_SpCG1C_ScCTK2-like_rpt2; 1.
DR Gene3D; 1.10.472.10; Cyclin-like; 2.
DR InterPro; IPR013763; Cyclin-like_dom.
DR InterPro; IPR036915; Cyclin-like_sf.
DR InterPro; IPR043198; Cyclin/Ssn8.
DR InterPro; IPR006671; Cyclin_N.
DR PANTHER; PTHR10026:SF112; CTD KINASE SUBUNIT BETA; 1.
DR PANTHER; PTHR10026; CYCLIN; 1.
DR Pfam; PF00134; Cyclin_N; 1.
DR SMART; SM00385; CYCLIN; 2.
DR SUPFAM; SSF47954; Cyclin-like; 2.
PE 3: Inferred from homology;
KW Activator {ECO:0000256|ARBA:ARBA00023159};
KW Cyclin {ECO:0000256|RuleBase:RU000383};
KW Reference proteome {ECO:0000313|Proteomes:UP000037696};
KW Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT DOMAIN 65..164
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT DOMAIN 177..263
FT /note="Cyclin-like"
FT /evidence="ECO:0000259|SMART:SM00385"
FT REGION 299..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 382 AA; 43205 MW; EBE8041263524A4E CRC64;
MARNMRDESP RGGSTLEFGL STPAIHPSFI QVANPYIFEQ TIENCIEAMS VNPLRETSLR
LQGVAWIDSV RRALNLPIRT FDTAVGYYHR FRLVHPDNEY NWTDAAAAAL FTACKIEDTL
KKSRDIVCAA YNLKLAPSEH LSADDPMFES HARGIIGLER LMLEASGFDF RTRHPHKTLM
KLGRHYGLLQ NSEVSNLAYR ISSDLYRTFA PIKQNSSTMA FSCLELAGRL LDQRVEQVES
GLDYVQWSTS RAEIMETLFD LLELYTHHRS LTAVGSEFPA DRFLTVRIPL NQEASEHNIP
RYQPWIGQPP KPSNGAGTND QDTPRPAHPL TPIAANGDRQ RTGERGRDAA VRFMLDPACA
DEERRQVAAY FKVEMEEYEV DG
//
