ID A0A0M8SFG6_9ACTN Unreviewed; 388 AA.
AC A0A0M8SFG6;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=glycerophosphodiester phosphodiesterase {ECO:0000256|ARBA:ARBA00012247};
DE EC=3.1.4.46 {ECO:0000256|ARBA:ARBA00012247};
GN ORFNames=ADK54_39295 {ECO:0000313|EMBL:KOU34962.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU34962.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a sn-glycero-3-phosphodiester + H2O = an alcohol + H(+) + sn-
CC glycerol 3-phosphate; Xref=Rhea:RHEA:12969, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30879, ChEBI:CHEBI:57597,
CC ChEBI:CHEBI:83408; EC=3.1.4.46;
CC Evidence={ECO:0000256|ARBA:ARBA00029315};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU34962.1}.
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DR EMBL; LGDD01000341; KOU34962.1; -; Genomic_DNA.
DR RefSeq; WP_053730620.1; NZ_LGDD01000341.1.
DR AlphaFoldDB; A0A0M8SFG6; -.
DR PATRIC; fig|1415557.3.peg.8643; -.
DR OrthoDB; 9758957at2; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd08602; GDPD_ScGlpQ1_like; 1.
DR Gene3D; 3.20.20.190; Phosphatidylinositol (PI) phosphodiesterase; 1.
DR InterPro; IPR030395; GP_PDE_dom.
DR InterPro; IPR017946; PLC-like_Pdiesterase_TIM-brl.
DR InterPro; IPR006311; TAT_signal.
DR PANTHER; PTHR43620:SF7; GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE GDPD6; 1.
DR PANTHER; PTHR43620; GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE; 1.
DR Pfam; PF03009; GDPD; 1.
DR SUPFAM; SSF51695; PLC-like phosphodiesterases; 1.
DR PROSITE; PS51704; GP_PDE; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..33
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 34..388
FT /note="glycerophosphodiester phosphodiesterase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5005822476"
FT DOMAIN 54..382
FT /note="GP-PDE"
FT /evidence="ECO:0000259|PROSITE:PS51704"
SQ SEQUENCE 388 AA; 42361 MW; FA6CC0D5A3E0570B CRC64;
MDKRHEPGRR AVLGAAALGT GAAVLAGAGQ ANAAGTGPAD RSAPAGAPAK LPVPFVIGHR
GASGYRPEHT FGSYQLALDM GADVIEAGDL VPTKDGHLVC RHEPDISATT DVADHHEFAG
RRTTKTVDGT KITGWFTEDF TLAELKTLRA KERIPDVRQH NTMYNGHWEV PTFEEVLQWA
EREGRRRGRP IWIYPETKHP TYFRKLGLGI EEPLAKLLRR YGRHTAHAPN ILQSFEPSSL
KRLSELGVKC PKTVLLDEPS VRPADFVESG DPRTTADLLK PEGLKWIAGF AQGIGPWLPQ
IIAQDGQGNL GKPTTLVRDA HAAGLFLTPY TVRNENNFLP LDFRVGKNPG DYGNALAYFK
ALFATGIDGL FSDDPDTALL AAAEFRRR
//
