ID A0A0M8SR84_9ACTN Unreviewed; 486 AA.
AC A0A0M8SR84;
DT 09-DEC-2015, integrated into UniProtKB/TrEMBL.
DT 09-DEC-2015, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE SubName: Full=Aldehyde dehydrogenase {ECO:0000313|EMBL:KOU41495.1};
GN ORFNames=ADK54_20615 {ECO:0000313|EMBL:KOU41495.1};
OS Streptomyces sp. WM6378.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1415557 {ECO:0000313|EMBL:KOU41495.1, ECO:0000313|Proteomes:UP000037774};
RN [1] {ECO:0000313|Proteomes:UP000037774}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WM6378 {ECO:0000313|Proteomes:UP000037774};
RA Ju K.-S., Doroghazi J.R., Metcalf W.W.;
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KOU41495.1}.
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DR EMBL; LGDD01000268; KOU41495.1; -; Genomic_DNA.
DR RefSeq; WP_053727136.1; NZ_LGDD01000268.1.
DR AlphaFoldDB; A0A0M8SR84; -.
DR PATRIC; fig|1415557.3.peg.4592; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000037774; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07139; ALDH_AldA-Rv0768; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR42804; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR42804:SF1; ALDEHYDE DEHYDROGENASE-RELATED; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 23..477
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 253
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 486 AA; 51644 MW; 01802CE3F100CA89 CRC64;
MTELVEHGQL FIGGELTDPL GSDVIEVISP HTEQVIGRVP HASRADVDRA VAAARKSFDE
GPWARATPEE RIEVVTRIKD AILVRHEEIA KSISSQNGSP YSWSVLAQAL GAMMVWDSAI
TVARQFPYEE RRSGALGPIL VRREPVGVVA AVVPWNVPQF VAAAKLGPAL LTGCSVILKP
SPESPLDSYI LGEIAAEAGL PEGVLSILPA DREVSEYLVG HPGIDKVSFT GSVAAGKRVM
EVAARNLTRV TLELGGKSAA VILPDADLAA TVAGVVPAAW MNNGQACVAQ TRILAPRSRY
DEIAEAFAAA AGALVVGDPL DAATQVGPLV AKRQQQRSLD YIRIGQEEGA KILTGGGRPA
GLDRGWYVEP TLFGGVDNTM RIAREEIFGP VICLLPYGDE AEALRIANDS EYGLSGSVWT
GDVEHGIDFG RKVRTGTFNV NTFSLDMLGP FGGYKSSGLG REFGPEGFSE YLEHKMIHLP
AGHGGE
//
